86138-76-3

Upstream product

• 67-56-1 methanol 
• 86138-88-7 (2R,3R,6S)-3-Hydroxy-6-((R)-2-hydroxy-2-phenyl-ethyl)-2-prop-1-ynyl-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 86138-81-0 (2R,6S)-3-Oxo-6-(2-oxo-2-phenyl-ethyl)-2-prop-1-ynyl-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 86138-85-4 (2R,3S,6S)-3-Hydroxy-6-(2-oxo-2-phenyl-ethyl)-2-prop-1-ynyl-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 

Downstream Products

• 86138-75-2 (3aR,5R,7aR)-5-((R)-2-Hydroxy-2-phenyl-ethyl)-2-methoxy-2-methyl-hexahydro-furo[3,2-b]pyridine-4-carboxylic acid methyl ester 
• 86138-73-0 (S)-2-((3aS,5S,7aS)-2-Methoxy-2,4-dimethyl-octahydro-furo[3,2-b]pyridin-5-yl)-1-phenyl-ethanol 
• 77784-07-7 (+/-)-sedacryptine 

Relevant academic research and scientific papers

APPLICATION OF THE OXYGENATIVE NUCLEOPHILE INTRODUCTION REACTION TO 1-ALKOXYCARBONYL-2-ALKYNYL-1,2-DIHYDROPYRIDINES. A FACILE SYNTHESIS OF (+/-)-SEDACRYPTINE

A Sedum alkaloid, (+/-)-sedacryptine (17) was effectively synthesized from the compound (3g), one of the products (3a-3l) derived from 2-alkynyl-1,2-dihydropyridine derivatives (2) by application of our oxygenative nucleophile introduction reaction.