861393-66-0

Basic information

• Product Name: N-[1-(1H-Benzotriazol-1-yl)-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide
• Synonyms: N-[1-(1H-Benzotriazol-1-yl)-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide;N-(1-(1H-benzo[d][1,2,3]triazol-1-yl)-2,2-diMethylpropyl)-2-(3,4-diMethoxyphenyl)acetaMide
• CAS NO: 861393-66-0
• Molecular Formula: C₂₁H₂₆N₄O₃
• Molecular Weight: 382.45614
• Mol File: 861393-66-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.19
• CAS DataBase Reference: N-[1-(1H-Benzotriazol-1-yl)-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[1-(1H-Benzotriazol-1-yl)-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide(861393-66-0)
• EPA Substance Registry System: N-[1-(1H-Benzotriazol-1-yl)-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide(861393-66-0)

Safety Data

• Hazardous Substances Data: 861393-66-0(Hazardous Substances Data)

Upstream product

• 10313-60-7 3,4-dimethoxyphenylacetyl chloride 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 95-14-7 1,2,3-Benzotriazole 
• 5663-56-9 2-(3,4-dimethoxyphenyl)acetamide 
• 630-19-3 pivalaldehyde 

Downstream Products

• 861393-24-0 N-[1-({(cyanoimino)[(2,6-dimethoxy-3-pyridinyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 
• 861393-28-4 N-[1-({(cyanoimino)[(5-quinolinyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 
• 861393-18-2 N-[1-({(cyanoimino)[(2,5-dimethylphenyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 
• 861393-20-6 N-(1-{[[(5-chloro-2-fluorophenyl)amino](cyanoimino)methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide 
• 861393-16-0 N-[1-({(cyanoimino)[(2,5-difluorophenyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 
• 861393-19-3 N-[1-({(cyanoimino)[(2,4,6-trifluorophenyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 
• 861393-22-8 N-(1-{[[(2-chloro-3-pyridinyl)amino](cyanoimino)methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide 
• 861393-21-7 N-[1-({(cyanoimino)[(2-methoxy-3-pyridinyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 
• 1158074-19-1 N-[1-({(cyanoimino)[(2-fluorophenyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 
• 1158074-20-4 N-[1-({(cyanoimino)[(2,6-difluorophenyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 
• 1158074-21-5 N-[1-({(cyanoimino)[(2,4-difluorophenyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 
• 1158074-22-6 N-[1-({(cyanoimino)[(5-isoquinolinyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 
• 1158074-23-7 N-[1-({(cyanoimino)[(2-methyl-3-pyridinyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 
• 1158074-25-9 N-[1-({(cyanoimino)[(2,3-difluorophenyl)amino]methyl}amino)-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide 

Relevant articles and documents

Synthesis, characterization and cardioprotective activity of some novel benzotriazole and pyrazole derivatives

A series of N-(1-(1H-benzo[d]) [1,2,3]triazol-1-yl)-2,2-dimethyl propyl)-2-(substituted phenyl) acetamide derivatives and methyl 5-((4- (2,5-disubstituted phenyl) furan-2 carboxylate derivatives are prepared from different substituted aryl carboxylic acids, phenyl acetic acid and cinnamic acid, respectively. All the synthesized compounds are investigated for cardioprotective activity by ischemia reperfusion method, while all the compounds show significant activity.

Cyanoamidine P2X7 antagonists for the treatment of pain

Novel cyanoamidines compounds of formula (I) and (II) and their derivatives wherein R1-R12 are as defined in the specification act as antagonists of the P2X7 receptor. These compounds are particularly useful in the treatment of pain, inflammation and neurodegeneration states.