86148-27-8

Usage

Uses

Used in Organic Chemistry:
1-methyl-4-[2-(4-methylphenyl)sulfanylethynylsulfanyl]benzene is used as a reactive intermediate for the synthesis of various organic compounds due to its unique structure and reactivity.
Used in Materials Science:
MPTSESB is utilized as a building block in the development of novel materials with specific properties, such as optoelectronic materials, due to its structural features and potential for molecular engineering.
Used in Pharmaceutical Research:
1-methyl-4-[2-(4-methylphenyl)sulfanylethynylsulfanyl]benzene is used as a candidate for drug discovery and development, given its potential biological activity and the possibility of its interaction with biological targets for therapeutic purposes.
Safety Considerations:
Due to the complexity of its structure, MPTSESB requires careful handling and adherence to proper safety measures when used in laboratory and industrial settings to ensure the safety of personnel and the integrity of the compound.

Upstream product

• 4526-50-5 (E)-1,2-dichloro-1,2-bis-p-tolylsulfanyl-ethene 
• 106-45-6 para-thiocresol 
• 5324-85-6 1,2-bis-p-tolylsulfanyl-ethene 
• 32294-60-3 diphenyl ditelluride 
• 40976-96-3 tolyl 2,2-dichlorovinyl sulfide 
• 430-58-0 1,2-dichloro-2-fluoroethene 
• 7572-29-4 dichloroethyne 
• 540-49-8 cis+trans-dibromoethylene 
• 39549-10-5 1-[(4-methylphenyl)sulfanyl]pyrrolidine-2,5-dione 
• 65032-27-1 ethynylmagnesium chloride 

Downstream Products

• 98111-37-6 p-tolylsulfanyl-thioacetic acid S-p-tolyl ester 
• 103-19-5 di(p-tolyl) disulfide 
• 3996-29-0 2-[(4-methylphenyl)thio]acetic acid 
• 39837-43-9 1,2-bis-(toluene-4-sulfonyl)-1-p-tolylsulfanyl-ethane 
• 39837-39-3 1,1,2-tris-(toluene-4-sulfonyl)-ethane 
• 34726-90-4 trans-1-(toluene-4-sulfonyl)-2-p-tolylsulfanyl-ethene 
• 32018-25-0 1-(toluene-4-sulfonyl)-2-p-tolylsulfanyl-ethane 
• 3937-96-0 tosylacetic acid 
• 5324-85-6 1,2-bis-p-tolylsulfanyl-ethene 
• 95432-39-6 p-tolylsulfanyl-acetaldehyde di-p-tolyldithioacetal 
• 21213-28-5 1,2-bis-(toluene-4-sulfonyl)-ethene 
• 100557-90-2 (toluene-4-sulfonyl)-acetaldehyde phenylhydrazone 
• 144488-85-7 1-(toluene-4-sulfinyl)-2-(toluene-4-sulfonyl)-ethene 
• 109410-45-9 toluene-4-sulfinic acid ; compound with phenylhydrazine 

Relevant academic research and scientific papers

Substituted alkyne synthesis under nonbasic conditions: copper carboxylate-mediated, palladium-catalyzed thioalkyne-boronic acid cross-coupling.

[figure: see text] A new methodology for the synthesis of substituted alkynes is described. In the presence of copper(I) thiophene-2-carboxylate (CuTC) or copper (I) 3-methylsalicylate (CuMeSal), the palladium-catalyzed cross-coupling of thioalkyne derivatives with boronic acids affords functionalized alkynes in yields ranging from 39 to 91%. This coupling occurs efficiently under mild, nonbasic conditions with a wide variety of thioalkynes and boronic acids, providing a reaction complementary to the Sonogashira protocol.

Phase transfer catalysis in synthesis of organylthio(organyltelluro) acetylenes

Phase transfer reaction of diorganyl ditellurides with organyl-2,2-dichlorovinyl sulfides, using as phase transfer catalysts benzyltriethylammonium chloride or 18-crown-6 ether, was used as a new general method to prepare organylthio(organyltelluro)acetylenes R-S-C≡C-Te-R′. The organyltellurolate anion formed in the presence of NaOH is the reaction intermediate.

A New Approach to the Synthesis of Symmetrical Bis(organylchalcogeno)acetylenes: Scope and Limitations

A new general method to prepare bis(organylchalcogeno)acetylenes R-Y-CC-Y-R (Y = S, Se, Te) by dehydrochlorination of the corresponding 1,2-bis(organylchalcogeno)chloroethylenes R-Y-CH=CCl-Y-R with tert-BuOK/tert-BuOH and/or KOH/DMSO is developed.Dechlorination of 1,2-bis(organylchalcogeno)-1,2-dichloroethylenes R-Y-CCl=CCl-Y-R (Y = S, Se, Te) with BuLi in ether or THF is effective only for sulfur derivatives.With Y = Se and alkyl substituents, substitution of the chlorine atom by a butyl group takes place giving rise to 5,6-bis(alkylseleno)dec-5-ene .With aryl substituents, an attack of the ArSe-group by the Bu-radical is observed leading to an aryl butyl selenide.In the case of the tellurium compound Ph-Te-CCl=CCl-Te-Ph, there is a competition between dechlorination to give Ph-Te-CC-Te-Ph, and substitution to produce the phenyl butyl telluride. - Keywords: bis(organylchalcogeno)acetylene; 1,2-bis(organylchalcogeno)chloroethylene; 1,2-bis(organochalcogeno)-1,2-dichloroethylene.

NUCLEOPHILIC REACTIONS AT A VINYLIC CENTER. XXVIII. FLUOROCHLOROETHENES AND FLUOROBROMOETHENES IN REACTIONS WITH SODIUM ALCOHOLATES AND ARENETHIOLATES

During the reaction of halogenoethenes (Z+E)-CHX=CFX with sodium methoxide and with sodium p-thiocresolate in methanol initial attack by the nucleophilic takes place at the carbon atom attached to the fluorine atom.In the reactions with sodium methoxide the intermediate monosubstitution products are more reactive than the initial halogenoethenes, and the main reaction products are the ortho esters CHXYC(OMe)3.An "element effect", i.e., concurrent substitution of F and Cl(Br) in the reaction with sodium methoxide, was discovered.With sodium p-thiocresolate trifluorochloroethene gives the product from substitution of the chlorine atom and a small amount of the addition product as impurity.The other ethenes give substitution, addition, and halogenophilic reduction products and also the products from further transformations (hydrolysis and decarboxylation).

A broad scope highly efficient synthesis of bis(R-thio)acetylenes

Treatment of dichloroacetylene with two equivalents of a thiol and two equivalents of potassium hydride in THF solution affords the corresponding bis(R-thio)acetylene in high yield.