86149-00-0Relevant academic research and scientific papers
Synthesis of some new 2-(phenoxyacetylthio)-3-aryl-6-bromo- or 6,8-dibromoquinazoline-4(3H)-ones as possible AChE inhibitors
Hajela Km.,Sengupta,Shanker,Doval
, p. 431 - 434 (2007/10/02)
Sixteen new 2-(phenoxyacetylthio)-3-aryl-6-bromo- or -6,8-dibromoquinazolines were synthesized by condensation of various phenoxyacetyl chlorides with mercaptoquinazolines. Their inhibitory properties towards choline esterase and their bactericidal activities were studied in vitro. Nine of the compounds exhibited (>50%) choline esterase inhibition, whereas the antibacterial screening showed moderate results.
