86152-46-7Relevant academic research and scientific papers
SYNTHESIS OF C-AZOYLACETIC ACID ESTERS BASED ON CARBETHOXYETHYLACETIMIDATE
Kiseleva, V. V.,Gakh, A. A.,Fainzil'berg, A. A.
, p. 1888 - 1895 (1990)
Preparative methods were developed for synthesizing 1,2,4-triazolyl-1,3,4-oxadiazolyl-, 1,2,4-oxadiazolyl-, and 1,3,4-thiadiazolylacetic acid esters based on carbethoxyethylacetimidate chlorohydrate.
Trinitromethyl-substituted 5-nitro- or 3-azo-1,2,4-triazoles: Synthesis, characterization, and energetic properties
Thottempudi, Venugopal,Gao, Haixiang,Shreeve, Jeanne M.
experimental part, p. 6464 - 6471 (2011/06/10)
Various new polynitro-1,2,4-triazoles containing a trinitromethyl group were synthesized by straightforward routes. These high nitrogen and oxygen-rich compounds were fully characterized using IR and multinuclear NMR spectroscopy, elemental analysis, natural bonding orbital (NBO) analysis, and differential scanning calorimetry (DSC) and, in the case of 12, with single crystal X-ray structuring. The heats of formation for all compounds were calculated with Gaussian 03 (revision D.01) and then combined with experimentally determined densities to determine detonation pressures (P) and velocities (D) of the energetic materials (Cheetah 5.0). They exhibit high density, good thermal stability, acceptable oxygen balance, positive heat of formation, and excellent detonation properties, which, in some cases, are superior to those of TNT, RDX, and HMX.
Design, synthesis and molecular modeling study of acylated 1,2,4-triazole-3-acetates with potential anti-inflammatory activity
Abdel-Megeed, Ashraf M.,Abdel-Rahman, Hamdy M.,Alkaramany, Gamal-Eldien S.,El-Gendy, Mahmoud A.
experimental part, p. 117 - 123 (2009/04/07)
The present investigation is concerned with the synthesis of different acylated 1,2,4-triazole-3-acetates with the objective of discovering novel and potent anti-inflammatory agents. Structures of the synthesized compounds were elucidated by spectral and
Synthesis of esters and amides of 5-amino-1,2,4-triazole-3-carboxylic and 5-amino-1,2,4-triazol-3-ylacetic acids
Chernyshev,Chernysheva,Taranushich
, p. 783 - 786 (2008/02/05)
Various synthetic routes to esters and amides of 5-amino-1,2,4-triazole-3- carboxylic and 5-amino-1,2,4-triazol-3-ylacetic acids were examined. Pleiades Publishing, Inc., 2006.
Synthesis and Some Transformations of 3-Substituted 1,2,4-Triazole-5-acetic Acids
Kofman, T. P.,Uvarova, T. A.,Kartseva, G. Yu.
, p. 240 - 244 (2007/10/02)
The reaction of aminoguanidine hydrogen carbonate with malonic acid gave 5-amino-1,2,4-triazole-5-acetic acid whose further transformations resulted in azo and nitro 1,2,4-triazole derivatives containing carboxy and ethoxycarbonylmethyl groups at the ring carbon atom; their nitrosation afforded derivatives of 3-nitro-1,2,4-triazol-5-yl(hydroxyimino)acetic acid.
