861640-71-3Relevant articles and documents
Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity
Shi, Zhen-Dan,Liu, Hongpeng,Zhang, Manchao,Worthy, Karen M.,Bindu, Lakshman,Yang, Dajun,Fisher, Robert J.,Burke Jr., Terrence R.
, p. 4200 - 4208 (2007/10/03)
Although considerable effort has been devoted to developing Grb2 SH2 domain-binding antagonists, important questions related to ligand specificity, and identification of intracellular targets remain unanswered. In order to begin addressing these issues, t