861640-63-3

Upstream product

• 861640-62-2 (4S)-3-[3-(5-(2-(trimethylsilyl)ethyl)oxy-1-naphthalenyl)-1-oxo-2-propan-1-yl]-4-phenyl-2-oxazolidinone 
• 556-56-9 allyl iodid 
• 259529-54-9 (4S)-3-(1-oxo-2-propen-1-yl)-4-phenyl-1,3-oxazolidin-2-one 
• 2916-68-9 2-(Trimethylsilyl)ethanol 
• 861640-61-1 (4S)-3-[3-(5-(2-(trimethylsilyl)ethyl)oxy-1-naphthalenyl)-1-oxo-2-propen-1-yl]-4-phenyl-2-oxazolidinone 
• 861640-60-0 (4S)-3-[3-(5-hydroxy-1-naphthalenyl)-1-oxo-2-propen-1-yl]-4-phenyl-2-oxazolidinone 
• 52927-23-8 5-bromo-1-naphthol 

Downstream Products

• 861640-71-3 C₆₇H₉₆N₇O₁₃PS 
• 861640-69-9 (βS,γS)-β-[[1-[[(1S)-3-amino-1-[[(2S)-2-(5-hydroxy-1-naphthalenylmethyl)-4-pentenyl]aminocarbonyl]-3-oxopropyl]aminocarbonyl]cyclohexyl]aminocarbonyl]-4-[4-[bis(tert-butoxy)phosphoryl]methyl]-γ-ethenylbenzenebutanoic acid 1,1-dimethylethyl ester 
• 861640-70-2 (9S,10S,11E,14S,18S)-18-(2-amino-2-oxoethyl)-10-[[4-[bis(1,1-dimethylethoxy)phosphoryl]methyl]phenyl]-14-(1-(5-hydroxy)naphthalenylmethyl)-8,17,20-trioxo-7,16,19-triazaspiro[5.14]eicos-11-en-9-acetic acid 1,1-dimethylethyl ester 
• 861640-68-8 (2S)-2-[[(1-aminocyclohexyl)carbonyl]amino]-N¹-[(2S)-2-(5-hydroxy-1-naphthalenylmethyl)-4-pentenyl]butanediamide 

Relevant academic research and scientific papers

Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity

Although considerable effort has been devoted to developing Grb2 SH2 domain-binding antagonists, important questions related to ligand specificity, and identification of intracellular targets remain unanswered. In order to begin addressing these issues, t