861657-83-2Relevant academic research and scientific papers
Exploiting the regioselectivity of pyroglutamate alkylations for the synthesis of 6-azabicyclo[3.2.1]octanes and 4-azabicyclo[3.3.0]octanes
Masschelein, Kurt G.R.,Stevens, Christian V.,Dieltiens, Nicolai,Claeys, Diederica D.
, p. 4712 - 4724 (2007)
Depending on the N-protecting group of pyroglutamates, the reactivity can be directed to the formation of 6-azabicyclo[3.2.1]octanes or 4-azabicyclo[3.3.0]octanes, which are conformationally restricted glutamate analogues.
