861695-54-7Relevant academic research and scientific papers
Glycopeptides of the V3 loop of gp120 and derivatives; preparation and applications as HIV-1 vaccines.
-
Page/Page column 3; 4, (2010/11/25)
A method of making a synthetic glycopeptide, by addition of a synthetic oligosaccharide oxazoline to a GlcNAc-containing peptide precursor in the presence of an enzyme selected from among Endo-A and Endo-M. In a specific implementation, the method is util
Highly efficient endoglycosidase-catalyzed synthesis of glycopeptides using oligosaccharide oxazolines as donor substrates
Li, Bing,Zeng, Ying,Hauser, Steven,Song, Haijing,Wang, Lai-Xi
, p. 9692 - 9693 (2007/10/03)
A highly efficient chemoenzymatic synthesis of N-glycopeptides was achieved. It was found that using synthetic oligosaccharide oxazolines, the mimics of the presumed oxazolinium ion intermediate formed in a retaining mechanism of substrate-assisted cataly
