80035-36-5

Basic information

• Product Name: Benzyl 2-Deoxy-2-phthalimido-3,6-di-O-benzyl--D-glucopyranoside
• Synonyms: Benzyl 2-Deoxy-2-phthalimido-3,6-di-O-benzyl--D-glucopyranoside;PhenylMethyl 2-Deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3,6-bis-O-(phenylMethyl)-β-D-glucopyranoside;Benzyl 2-Deoxy-2-phthalimido-3,6-di-O-benzyl-2-D-glucopyranoside
• CAS NO: 80035-36-5
• Molecular Formula: C₃₅H₃₃NO₇
• Molecular Weight: 579.63902
• Product Categories: Carbohydrates & Derivatives
• Mol File: 80035-36-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 732.101°C at 760 mmHg
• Flash Point: 396.56°C
• Appearance: /
• Density: 1.339g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.662
• Solubility: Acetone, Dichloromethane, Ethyl Acetate, Methanol
• PKA: 12.92±0.70(Predicted)
• CAS DataBase Reference: Benzyl 2-Deoxy-2-phthalimido-3,6-di-O-benzyl--D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl 2-Deoxy-2-phthalimido-3,6-di-O-benzyl--D-glucopyranoside(80035-36-5)
• EPA Substance Registry System: Benzyl 2-Deoxy-2-phthalimido-3,6-di-O-benzyl--D-glucopyranoside(80035-36-5)

Safety Data

• Hazardous Substances Data: 80035-36-5(Hazardous Substances Data)

Usage

Chemical Properties

Colourless Oil

InChI:InChI=1/C35H33NO7/c37-31-29(23-40-20-24-12-4-1-5-13-24)43-35(42-22-26-16-8-3-9-17-26)30(32(31)41-21-25-14-6-2-7-15-25)36-33(38)27-18-10-11-19-28(27)34(36)39/h1-19,29-32,35,37H,20-23H2/t29?,30?,31-,32-,35-/m1/s1

Upstream product

• 191482-37-8 benzyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranoside 
• 159734-70-0 phenyl 3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside 
• 100-51-6 benzyl alcohol 
• 80035-34-3 2-((4aR,6R,7R,8R,8aS)-6,8-Bis-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-isoindole-1,3-dione 
• 80035-33-2 benzyl 4,6-O-benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranoside 
• 33868-53-0 tributylstannyl benzyl ether 
• 156520-24-0 Benzyl 3-O-benzyl-2-desoxy-4,6-O-isopropylidene-2-phthalimido-β-D-glucopyranoside 
• 151266-88-5 Benzyl 2-desoxy-4,6-O-isopropylidene-2-phthalimido-β-D-glucopyranoside 
• 80035-31-0 benzyl 2-phthalimido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside 
• 80035-32-1 benzyl 2-deoxy-2-phthalimido-β-D-glucopyranoside 
• 10022-13-6 1,3,4,6-tetra-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranose 
• 100-39-0 benzyl bromide 
• 80035-35-4 benzyl 3-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 

Downstream Products

• 188302-08-1 C₆₁H₆₇NO₂₄ 
• 156520-27-3 Benzyl 2-allyloxycarbonylamino-3,6-di-O-benzyl-2-desoxy-β-D-glucopyranoside 
• 1228931-49-4 benzyl 3,6-di-O-benzyl-2-deoxy-2-phthalimido-4-O-(3,6-di-O-benzyl-2,4-dideoxy-2-phthalimido-β-D-glucopyranosyl)-β-D-glucopyranoside 
• 62867-63-4 benzyl 2-acetamido-2-deoxy-3,6-di-O-benzyl-β-D-glucopyranoside 
• 89067-93-6 benzyl O-(3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 
• 89067-92-5 benzyl O-(4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 
• 1342309-90-3 benzyl 2-O-benzyl-4,6-O-benzylidene-3-O-p-methoxybenzyl-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 
• 1342309-92-5 benzyl 2-O-benzyl-6-O-tert-butyldimethylsilyl-3-O-p-methoxybenzyl-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 
• 1342309-91-4 benzyl 2-O-benzyl-3-O-p-methoxybenzyl-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 

Relevant articles and documents

SYNTHESIS AND USE OF ISOTOPICALLY-LABELLED GLYCANS

Isotopically-labelled glycans and their synthesis and use as internal standards in the analysis by mass spectrometry of glycan mixtures is described. The methods of synthesis described herein may be used conveniently to prepare libraries of heavy glycans for use in the qualitative and quantitative identification of glycans in natural samples.

MENINGOCOCCUS SEROGROUP X CONJUGATE

The invention provides a conjugate of a Neisseria meningitidis serogroup X capsular polysaccharide and a carrier molecule. The conjugate is typically made by (a) oxidising a primary hydroxyl group in the capsular polysaccharide, to give an oxidised polysaccharide with an aldehyde group; and (b) coupling the oxidised polysaccharide to a carrier molecule via the aldehyde group, thereby giving the conjugate. The conjugate may be part of an immunogenic composition. This composition may comprise one or more further antigens, particularly capsular polysaccharides from serogroups A, W135, C and Y and conjugated forms thereof. The composition may be in an aqueous formulation. The composition is useful as a vaccine, e.g. for raising an immune response in a mammal. The invention also provides processes for making the conjugate.

RECTIVITE COMPAREE DE DIVERS ACCEPTEURS DE LA D-GLUCOSAMINE LORS DE LA SYNTHESE DE PRECURSEURS DU CHITOBIOSE

Six D-glucosamine derivatives, diversely substituted at the nitrogen atom, were tested as acceptors in glycosylation reactions with 1,3,4,6-tetra-O-acetyl-2-allyloxycarbonylamino-2-deoxy-β-D-glucopyranose (1) as the donor and trimethylsilyl trifluoromethanesulfonate as the promoter.The observed yields were high with 2-phthalimido- and 2-azido-D-glucosamine acceptors and more generally good with acceptors of the 1,6-anhydro-D-glucosamine series.The disaccharides benzyl 4-O-(3,4,6-tri-O-acetyl-2-allyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside (20), benzyl 4-O-(3,4,6-tri-O-acetyl-2-allyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-2-allyloxycarbonylamino-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside (21), 4-O-(3,4,6-tri-O-acetyl-2-allyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-1,6-anhydro-2-azido-3-O-benzyl-2-deoxy-β-D-glucopyranose (22), 4-O-(3,4,6-tri-O-acetyl-2-allyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-2-allyloxycarbonylamino-1,6-anhydro-3-O-benzyl-2-deoxy-β-D-glucopyranose (23), 2-acetamido-4-O-(3,4,6-tri-O-acetyl-2-allyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-1,6-anhydro-3-O-benzyl-2-deoxy-β-D-glucopyranose (24) and 2-acetamido-4-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-1,6-anhydro-3-O-benzyl-2-deoxy-β-D-glucopyranose (25) have thus been synthesized.