86170-17-4Relevant academic research and scientific papers
Synthesis of thioamides via one-pot A3-coupling of alkynyl bromides, amines, and sodium sulfide
Sun, Yadong,Jiang, Huanfeng,Wu, Wanqing,Zeng, Wei,Li, Jianxiao
supporting information, p. 700 - 707 (2014/01/06)
We herein describe a novel method for the synthesis of thioamides by a three component condensation of alkynyl bromides, amines, and Na 2S·9H2O. The developed method is applicable for a wide range of amines and alkynyl bromides bearing different functional groups furnishing the corresponding products in moderate to excellent yields. The Royal Society of Chemistry.
Scope of Organic Synthetic Reactions. Multivariate Methods for Exploring the Reaction Space. An Example with the Willgerodt-Kindler Reaction.
Carlson, Rolf,Lundstedt, Torbjoern
, p. 164 - 173 (2007/10/02)
New principles are presented by which the scope and limitations of synthetic reactions can be determined when substrates, reagents and solvents are allowed to vary sumaltaneously.The strategies are based on multivariate statistical methods: (a) Characteri
