861901-07-7

Upstream product

• 905830-92-4 tert-butyl (3S)-3-(3-(3-methoxypropoxy)-4-methoxybenzyl)-1-formyl-4-methylpentylcarbamate 
• 1774-47-6 trimethylsulfoxonium iodide 
• 656241-17-7 (2S,5R)-2,5-dihydro-3,6-dimethoxy-2-{(2S)-2-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-3-methylbutyl}-5-(1-methylethyl)pyrazine 
• 656241-36-0 methyl (2S,4S)-2-amino-4-[4-methoxy-3-(3-methoxypropoxy)benzyl]-5-methylhexanoate 
• 172900-74-2 [4-methoxy-3-(3-methoxypropoxy)-phenyl]methanol 
• 172900-73-1 4-(bromomethyl)-1-methoxy-2-(3-methoxypropoxy)-benzene 
• 172900-70-8 (R)-2-[4-methoxy-3-(3-methoxypropoxy)benzyl]-3-methylbutanol 
• 172900-75-3 4-methoxy-3-(3-methoxypropoxy)benzaldehyde 
• 108-12-3 isopentanoyl chloride 
• 145589-03-3 (R)-4-benzyl-3-(3-methylbutyryl)oxazolidin-2-one 
• 900811-38-3 (R)--4-(2-(iodomethyl)--3--methylbutyl)--1--methoxy-2--(3--methoxypropoxy)benzene 
• 172900-83-3 (1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester 

Downstream Products

• 905831-10-9 (4S,5S)-4-((S)-2-(3-(3-methoxypropoxy)-4-methoxybenzyl)-3-methylbutyl)-5-((phenylmethanesulfonyl)aminomethyl)oxazolidin-2-one 
• 861901-08-8 1-(4(S)-{2(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-3-methylbutyI}-2-oxooxazolidin-5(S)-ylmethyl)piperidin-2-one 
• 955020-83-4 3-((2S,3S,5S)-5-(3-(3-methoxypropoxy)-4-methoxybenzyl)-3-(tert-butoxycarbonylamino)-2-hydroxy-6-methylheptylamino)-4-(benzylamino)cyclobut-3-ene-1,2-dione 
• 955021-57-5 3-((2S,3S,5S)-5-(3-(3-methoxypropoxy)-4-methoxybenzyl)-3-(tert-butoxycarbonylamino)-2-hydroxy-6-methylheptylamino)-4-(N-methyl-N-(2-methylpentan-2-yl)amino)cyclobut-3-ene-1,2-dione 
• 955021-69-9 tert-butyl (2S,3S,5S)-5-(3-(3-methoxypropoxy)-4-methoxybenzyl)-1-(1,1-dioxo-4-(phenethylamino)-1,2,5-thiadiazol-3-ylamino)-2-hydroxy-6-methylheptan-3-ylcarbamate 
• 905831-20-1 (2S,3S,5S)-5-(3-(3-methoxypropoxy)-4-methoxybenzyl)-3-(tert-butoxycarbonylamino)-6-methyl-1-(N-pentyl-N-(tert-butoxycarbonyl)aminosulfonylamino)-heptan-2-ol 
• 861901-11-3 tert-butyl {1(S)-(2-amino-1(S)-hydroxyethyl)-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl}carbamate 
• 955021-64-4 3-((2S,3S,5S)-5-(3-(3-methoxypropoxy)-4-methoxybenzyl)-3-(tert-butoxycarbonylamino)-2-hydroxy-6-methylheptylamino)-4-hexylcyclobut-3-ene-1,2-dione 

Relevant academic research and scientific papers

1-HETEROCYCLYLAMINO-2-HYDROXY-3-AMINO-ω-ARYLALKANES

1-Heterocyclylamino-2-hydroxy-3-amino-?-arylalkanes of formula (I) and the salts thereof have renin-inhibiting properties and can be used as antihypertensive, medicinally active ingredients.

1-ACYLAMINO-2-HYDROXY-3-AMINO-W-ARYLALKANES AS RENIN INHIBITORS

1-Acylamino-2-hydroxy-3-amino-ω-arylalkanes of formula I. and the salts thereof, have renin-inhibiting properties and can be used as antihypertensive, medicinally active ingredients.

DIAMINO ALCOHOLS AND THEIR USE AS RENIN INHIBITORS

The application relates to novel amino alcohols of the general formula (I) where R, R1, R2, R3,R4, R5 and R6 each have the definitions illustrated in detail in the description, to a process for their preparation, and to the use of these compounds as medicines, in particular as renin inhibitors.