861902-93-4

Upstream product

• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 220235-68-7 (-)-(2S)-methyl 2-(p-methoxybenzyloxy)propanoate 
• 105-13-5 4-Methoxybenzyl alcohol 
• 824-94-2 p-methoxybenzyl chloride 
• 144401-98-9 (S)-2-(4-methoxybenzyloxy)propionic acid ethyl ester 
• 332837-94-2 (S)-2-(4-methoxybenzyloxy)propanoyl chloride 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 229647-61-4 (S)-2-((4-methoxybenzyl)oxy)propanoic acid 

Downstream Products

• 886582-87-2 (S)-4-(4-Methoxy-benzyloxy)-1-triethylsilanyl-pent-1-yn-3-one 
• 1058681-56-3 (S)-3-((4-methoxybenzyl)oxy)butan-2-one 
• 1058681-93-8 (2S,5S)-5-hydroxy-2-((4-methoxybenzyl)oxy)-6-methylhept-6-en-3-one 
• 1415121-62-8 (2S,5R)-5-hydroxy-2-((4-methoxybenzyl)oxy)-6-methylhept-6-en-3-one 
• 1058681-85-8 (2S,5S)-5-hydroxy-2-((4-methoxybenzyl)oxy)-6-methylheptan-3-one 
• 1415121-54-8 (2S,5R)-5-hydroxy-2-((4-methoxybenzyl)oxy)-6-methylheptan-3-one 
• 1415121-60-6 (2S,5S)-5-hydroxy-2-((4-methoxybenzyl)oxy)heptan-3-one 
• 1605305-44-9 C₁₆H₂₂O₃Si 

Relevant academic research and scientific papers

Diastereoselectivity in the boron aldol reaction of α-alkoxy and α,β-bis-alkoxy methyl ketones

In this work, using DFT calculations, we investigated the 1,4 and 1,5 asymmetric induction in boron enolate aldol reactions of α-alkoxy and α,β-bisalkoxy methyl ketones. We evaluated the steric influence of alkyl substituents at the α position and the stereoelectronic influence of the oxygen protecting groups at the α and β positions. Theoretical calculations revealed the origins of the 1,4 asymmetric induction in terms of the nature of the β-substituent. The synergistic effect between the α,β-syn and α,β-anti-bisalkoxy stereocenters was elucidated. In the presence of the β-alkoxy center, the reaction proceeds through the Goodman-Paton 1,5-stereoinduction model, experiencing a minor influence of the α-alkoxy center.

De novo synthesis of novel bacterial monosaccharide fusaminic acid

Fusobacterium nucleatum is an oral bacteria related to various types of diseases. As Gram-negative bacteria, lipopolysaccharide (LPS) of Fusobacterium nucleatum could be a potential virulence factor. Recently, the structure of O-antigen in LPS of Fusobact

Concise syntheses of (+)-macrosphelides A and B: Studies on the macro-ring closure strategy

Highly concise syntheses of (+)-macrosphelides A and B were accomplished in this study. The key feature of our synthetic route involved the direct three-carbon homologation of the readily available Weinreb amide 6 by the addition of a trans-vinylogous est

First asymmetric synthesis of a differentially silyl-protected tris(alkynyl)methyl methyl ether

The stereoselective synthesis of the differentially silyl-protected tris(alkynyl) methyl methyl ether, the first optically active trispropargylic alcohol derivative, was investigated. The asymmetric synthesis began with enantiometrically pure ethyl lactat

Concise syntheses of (+)-macrosphelides A and B

(Chemical Equation Presented) Unified and highly convergent total syntheses of (+)-macrosphelides A and B are described. Key features of the syntheses include (1) concise synthesis of the optically active δ-hydroxy-γ- keto α,β-unsaturated acid fragment vi