861906-64-1Relevant academic research and scientific papers
Tetrabutylammonium iodide-catalyzed phosphorylation of benzyl c-h bonds via a cross-dehydrogenative coupling (cdc) reaction
Xu, Jian,Zhang, Pengbo,Li, Xueqin,Gao, Yuzhen,Wu, Ju,Tang, Guo,Zhaoa, Yufen
, p. 3331 - 3335 (2014)
Phosphate esters play important roles as biological active principles and synthons in chemistry. An efficient metal-free approach for the synthesis of phosphate esters through sp3 C-H activation is described. By using tetrabutylammonium iodide (Bu4NI) as a catalyst and tert-butyl hydroperoxide (TBHP) as an oxidant, various toluene derivatives and phosphorus nucleophiles are tolerated in this transformation, affording the corresponding products in moderate to good yields.
O-Phosphination of Aldehydes/Ketones toward Phosphoric Esters: Experimental and Mechanistic Studies
Qian, Yanyan,Dai, Qiang,Li, Zhiming,Liu, Yu,Zhang, Junliang
supporting information, p. 4742 - 4748 (2020/06/29)
Addition of P-H species to carbonyl groups, namely the Pudovik reaction, normally delivers hydroxyl phosphorus compounds, along with phosphate byproducts in some cases. A few controllable systems starting from phosphites were set up to mainly provide the phosphates. Herein, we present a highly selective protocol starting from phosphonate precursors leading to phosphinate derivatives. Enantioenriched phosphinates were successfully achieved from chiral phosphine oxide precursors. Experimental and theoretical investigations were conducted to understand the mechanistic details.
Trimethylsilyl triflate mediated new carbon-carbon bond forming reactions between benzyl diphenylphosphinates and organosilicon compounds
Kobashi, Yohei,Minowa, Tomofumi,Mukaiyama, Teruaki
, p. 756 - 757 (2007/10/03)
The trimethylsilyl triflate mediated reaction of benzyl diphenylphosphinate with allyltrimethylsilane or trimethylsilyl enolate afforded the corresponding cross-coupling products in good yields. Copyright
