86196-81-8Relevant academic research and scientific papers
Azobisisobutyronitrile-Initiated Oxidative C-H Functionalization of Simple Alcohols with Diaryl(arylethynyl)phosphine Oxides: A Metal-Free Approach toward Hydroxymethyl Benzo[ b]phosphole Oxides and 6 H-Indeno[2,1- b]phosphindole 5-Oxide Derivatives
Guo, Jiami,Mao, Chenlu,Deng, Bin,Ye, Liyi,Yin, Yingwu,Gao, Yuxing,Tu, Song
, p. 6359 - 6371 (2020/07/14)
The first metal-free and facile radical addition/cyclization of simple alcohols with diaryl(arylethynyl)phosphine oxides has been described with azobisisobutyronitrile as a radical initiator, affording an efficient and one-pot procedure to access a new cl
Regioselective Synthesis of Heteroatom-Functionalized Cyclobutene-triflones and Cyclobutenones
Alcaide, Benito,Almendros, Pedro,Lázaro-Milla, Carlos
supporting information, p. 2630 - 2639 (2017/08/16)
The controlled metal-free synthesis of a vast variety of heteroatom-containing cyclobutene-triflones [bis(trifluoromethylsulfonyl)cyclobutenes] and cyclobutenones has been developed starting from heteroatom-substituted alkynes and a pyridinium salt (a latent Tf2C=CH2 source). This powerful methodology, involving cyclization reactions, allows for the selective preparation of oxygen-, nitrogen-, bromine-, chlorine-, iodine-, sulfur-, selenium-, tellurium-, phosphorus-, and silicon-functionalized cyclobutene derivatives. (Figure presented.).
Selective deprotection of Me3Si-/Ph2P(O)-protected arylalkynes: Methyl Grignard reagent-promoted dephosphorylation of Ph2P(O)-protected alkynes
Peng, Lifen,Xu, Feng,Shinohara, Kenta,Orita, Akihiro,Otera, Junzo
supporting information, p. 1610 - 1612 (2014/12/11)
A Ph2P(O)-protected alkyne underwent dephosphorylation by treatment with MeMgBr in THF with Me3Si-protection untouched. The dephosphorylation followed by a transition-metal-catalyzed coupling of the resulting terminal a lkyne with aryl halides was carried out in a one-pot manner to afford the desired coupling product. Selective deprotection of Me3Si-/Ph2P(O)-protected alkynes enabled facile syntheses of expanded π-systems such as cyclic phenyleneethyny lenes and unsymmetrically substituted ditriazol.
One-pot transformation of Ph2P(O)-protected ethynes: Deprotection followed by transition metal-catalyzed coupling
Peng, Lifen,Xu, Feng,Suzuma, Yoshinori,Orita, Akihiro,Otera, Junzo
, p. 12802 - 12808 (2014/01/17)
Ph2P(O)-protected ethynes were successfully transformed to arylethynes in one-pot manner through t-BuOK-catalyzed deprotection followed by Sonogashira coupling with aryl halide. The arylethynes were obtained similarly by Ph2P(O)-deprotection, stannylation of the resulting terminal ethynes, and Migita-Kosugi-Stille coupling. Deprotection followed by intramolecular Eglinton coupling could be carried out in one-pot to provide cyclic butadiynes.
Ph(O) group for protection of terminal acetylenes
Yang, Xin,Matsuo, Daisuke,Suzuma, Yoshinori,Fang, Jing-Kun,Xu, Feng,Orita, Akihiro,Otera, Junzo,Kajiyama, Shingo,Koumura, Nagatoshi,Hara, Kohjiro
supporting information; experimental part, p. 2402 - 2406 (2011/11/05)
A protecting group Ph(O) for terminal ethyne was newly developed. This protecting group can be introduced readily to terminal ethyne by CuI-catalyzed phosphination and subsequent oxidation with H Ph(O)-protected ethynes remained intact in Sonogashira coup
A Convenient and Direct Route to Phosphinoalkynes via Copper-Catalyzed Cross-Coupling of Terminal Alkynes with Chlorophosphanes
Afanasiev, Vladimir V.,Beletskaya, Irina P.,Kazankova, Marina A.,Efimova, Irina V.,Antipin, Mikhail U.
, p. 2835 - 2838 (2007/10/03)
A new efficient method to obtain various alkynylphosphanes R nP(≡R′)3-n [R = Ar, Alk, alkoxy, amido R′ = Ar, Het, Alk, CH2Z (Z = OMe, NMe2), n = 0-2] has been developed by means of cross-coupling reaction of chl
