862-26-0

Basic information

• Product Name: Z-VAL-TYR-OH
• Synonyms: Z-VAL-TYR-OH;Cbz-Val-Tyr-OH
• CAS NO: 862-26-0
• Molecular Formula: C₂₂H₂₆N₂O₆
• Molecular Weight: 414.45
• Mol File: 862-26-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: Z-VAL-TYR-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-VAL-TYR-OH(862-26-0)
• EPA Substance Registry System: Z-VAL-TYR-OH(862-26-0)

Safety Data

• Hazardous Substances Data: 862-26-0(Hazardous Substances Data)

Usage

Uses

Used in Biochemistry:
Z-VAL-TYR-OH is used as a research compound for studying protein synthesis and muscle metabolism due to its valine content.
Used in Pharmacology:
Z-VAL-TYR-OH is used as a precursor in the development of drugs targeting neurotransmitter and hormone production, given its tyrosine component.
Used in Medicine:
Z-VAL-TYR-OH is used as a potential therapeutic agent for conditions related to muscle metabolism and neurotransmitter imbalances, warranting further research for clinical applications.

Upstream product

• 15149-72-1 N-(N-benzyloxycarbonyl-L-valyl)-L-tyrosine methyl ester 
• 55378-69-3 (S)-2-Benzyloxycarbonylamino-3-methyl-butyric acid 3-ethylcarbamoyl-2-hydroxy-phenyl ester 
• 60-18-4 L-tyrosine 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 3417-91-2 L-tyrosine methyl ester HCl 
• 119153-86-5 C₁₆H₂₁NO₆ 

Downstream Products

• 101636-44-6 N-benzyloxycarbonyl-L-valyl=>L-tyrosyl=>L-valine methyl ester 
• 79190-57-1 1-[N-(N-benzyloxycarbonyl-L-valyl)-L-tyrosyl]-L-proline-benzyl ester 
• 3061-91-4 L-valyl-L-tyrosine 
• 90315-37-0 (S)-2-({(S)-1-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-phenyl-propionic acid ethyl ester 
• 3271-52-1 ZValTyrProOtBu 
• 41839-86-5 N-benzyloxycarbonyl-valyl->-tyrosyl->-valyl->-histidine methyl ester 
• 14331-00-1 N-benzyloxycarbonyl-L-valyl=>L-tyrosyl=>L-valyl=>L-histidyl=>L-prolyl=>L-phenylalanine-methyl ester 
• 90315-52-9 C₆₅H₈₂N₁₀O₁₄ 
• 90315-38-1 (S)-2-({(S)-1-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-phenyl-propionic acid 
• 90315-47-2 (2-{2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-phenyl-propionylamino]-acetylamino}-acetylamino)-acetic acid 
• 90315-46-1 (2-{2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-phenyl-propionylamino]-acetylamino}-acetylamino)-acetic acid ethyl ester 
• 90315-40-5 [((S)-1-{(S)-1-[(S)-2-({(S)-1-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-phenyl-propionyl]-pyrrolidine-2-carbonyl}-pyrrolidine-2-carbonyl)-amino]-acetic acid 
• 90315-39-2 [((S)-1-{(S)-1-[(S)-2-({(S)-1-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-phenyl-propionyl]-pyrrolidine-2-carbonyl}-pyrrolidine-2-carbonyl)-amino]-acetic acid benzyl ester 
• 90315-58-5 C₆₁H₇₆N₈O₁₂ 

Relevant articles and documents

Ecological base-conditioned preparation of dipeptides using unprotected α-amino acids containing hydrophilic side chains

The coupling reactions of 3-phenylpropanoic acid and Ncarboxybenzyl á-amino acids with unprotected á-amino acids containing hydrophilic side chains such as aliphatic alcohol, aromatic alcohol, thiol, carboxylic acid, and amide afforded the corresponding amides in 6696% yield without racemization via the corresponding mixed carbonic carboxylic anhydrides under basic conditions through an ecological green synthetic method.

STUDIES OF BITTER PEPTIDES FROM CASEIN HYDROLYZATE - VI. SYNTHESES AND BITTER TASTE OF BPIc (VAL-TYR-PRO-PHE-PRO-PRO-GLY-ILE-ASN-HIS) AND ITS ANALOGS AND FRAGMENTS.

In order to investigate the relationship between chemical structure and bitter taste, the bitter peptide BPIc (Val-Tyr-Pro-Phe-Pro-Pro-Gly-Ile-Asn-His) isolated from casein hydrolyzate by Minamiura et al. and its analogs and fragments were synthesized. BPIc, whose threshold value of bitter taste was 0. 05 mm, was found to be one of the most bitter compounds, like quinine and phenylthiourea. However, left bracket Gly**5**,**6 right bracket - and left bracket Gly**9**,**1**0 right bracket -BPIc, and N-terminal octa- and heptapeptide fragments of BPIc possessed much weaker bitterness than BPIc. The results suggested that 5,6-proline and the basic nature of C-terminal are necessary for the strong bitterness exhibited by BPIc.