15149-72-1

Basic information

• Product Name: N-CBZ-VAL-TYR METHYL ESTER
• Synonyms: Z-VAL-TYR METHYL ESTER;Z-VAL-TYR-OME;Z-L-VALYL-L-TYROSINE METHYL ESTER;N-BENZYLOXYCARBONYL-L-VALYL-L-TYROSINE METHYL ESTER;N-CBZ-VAL-TYR METHYL ESTER;methyl N-benzyloxycarbonyl-L-valyl-L-tyrosinate;Z-Val-try methyl ester;Cbz-Val-trymethylester
• CAS NO: 15149-72-1
• Molecular Formula: C₂₃H₂₈N₂O₆
• Molecular Weight: 428.48
• Product Categories: Amino Acid Derivatives;Dipeptides;Dipeptides and Tripeptides;Peptides
• Mol File: 15149-72-1.mol
• Article Data: 11

Chemical Properties

• Melting Point: 155.5-156℃
• Boiling Point: 654.7 °C at 760 mmHg
• Flash Point: 349.7 °C
• Appearance: /
• Density: 1.214 g/cm³
• Vapor Pressure: 9.66E-18mmHg at 25°C
• Refractive Index: 1.562
• Storage Temp.: −20°C
• PKA: 9.75±0.15(Predicted)
• CAS DataBase Reference: N-CBZ-VAL-TYR METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: N-CBZ-VAL-TYR METHYL ESTER(15149-72-1)
• EPA Substance Registry System: N-CBZ-VAL-TYR METHYL ESTER(15149-72-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 15149-72-1(Hazardous Substances Data)

Usage

General Description

N-CBZ-VAL-TYR METHYL ESTER, also known as N-Carbobenzyloxy-valyl-tyrosine methyl ester, is a chemical compound commonly used in peptide synthesis and pharmaceutical research. It is a protected form of the dipeptide valyl-tyrosine, where the amino acid side chains are protected with a carbobenzyloxy (CBZ) group to prevent unwanted reactions during peptide synthesis. N-CBZ-VAL-TYR METHYL ESTER is often used as an intermediate in the production of peptide-based drugs and pharmaceuticals, as well as in the study of enzyme kinetics and peptide structure-activity relationships. N-CBZ-VAL-TYR METHYL ESTER is a valuable tool in peptide chemistry and drug development due to its stability and ease of synthesis.

InChI:InChI=1/C23H28N2O6/c1-15(2)20(25-23(29)31-14-17-7-5-4-6-8-17)21(27)24-19(22(28)30-3)13-16-9-11-18(26)12-10-16/h4-12,15,19-20,26H,13-14H2,1-3H3,(H,24,27)(H,25,29)

Upstream product

• 10512-93-3 Z-Val-ONp 
• 3417-91-2 L-tyrosine methyl ester HCl 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 862-26-0 N^α-benzyloxycarbonylvalyltyrosine 
• 77-76-9 2,2-dimethoxy-propane 
• 67-56-1 methanol 
• 5992-90-5 N-benzyloxycarbonylvalyltyrosine hydrazide 
• 3496-11-5 2,5-dioxopyrrolidin-1-yl (2S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate 
• 1080-06-4 L-Tyr-OMe 

Downstream Products

• 5992-90-5 N-benzyloxycarbonylvalyltyrosine hydrazide 
• 54244-58-5 Valyl-tyrosine Methyl Ester 
• 862-26-0 N^α-benzyloxycarbonylvalyltyrosine 
• 7788-74-1 benzyl (1S)-1-({[(1S)-2-amino-1-(4-hydroxybenzyl)-2-oxoethyl]amino}carbonyl)-2-methylpropylcarbamate 
• 479207-58-4 (S)-2-[(S)-2-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-3-methyl-butyrylamino]-3-(4-hydroxy-phenyl)-propionic acid methyl ester 
• 479207-59-5 (S)-3-(4-Acetoxy-phenyl)-2-[(S)-2-((R)-2-tert-butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-3-methyl-butyrylamino]-propionic acid methyl ester 
• 479207-60-8 (S)-2-[(S)-2-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-3-methyl-butyrylamino]-3-(4-isobutyryloxy-phenyl)-propionic acid methyl ester 
• 479207-61-9 3-Methyl-but-2-enoic acid 4-{(S)-2-[(S)-2-((R)-2-tert-butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-3-methyl-butyrylamino]-2-methoxycarbonyl-ethyl}-phenyl ester 
• 479207-62-0 3-Methyl-butyric acid 4-{(S)-2-[(S)-2-((R)-2-tert-butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-3-methyl-butyrylamino]-2-methoxycarbonyl-ethyl}-phenyl ester 
• 479207-67-5 Benzoic acid 4-{(S)-2-[(S)-2-((R)-2-tert-butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-3-methyl-butyrylamino]-2-methoxycarbonyl-ethyl}-phenyl ester 
• 479207-63-1 Hexanoic acid 4-{(S)-2-[(S)-2-((R)-2-tert-butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-3-methyl-butyrylamino]-2-methoxycarbonyl-ethyl}-phenyl ester 
• 479207-64-2 (S)-2-[(S)-2-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-3-methyl-butyrylamino]-3-(4-phenylacetoxy-phenyl)-propionic acid methyl ester 

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