862073-79-8Relevant academic research and scientific papers
Opioid receptor ligands and methods for their preparation
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Page/Page column 12-13; Figure 2, (2008/06/13)
The invention provides novel compounds of formula I: that are opioid receptor ligands. The invention also provides pharmaceutical compositions comprising such compounds as well as methods for treating diseases associated with opioid receptor function by a
Neoclerodane diterpenes as a novel scaffold for μ opioid receptor ligands
Harding, Wayne W.,Tidgewell, Kevin,Byrd, Nathan,Cobb, Howard,Dersch, Christina M.,Butelman, Eduardo R.,Rothman, Richard B.,Prisinzano, Thomas E.
, p. 4765 - 4771 (2007/10/03)
Structural modification of salvinorin A, the active component of Salvia divinorum, has resulted in the synthesis of novel neoclerodane diterpenes with opioid receptor affinity and activity. We report in this study a nonnitrogenous neoclerodane diterpene w
