862129-81-5

Basic information

• Product Name: 3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester
• Synonyms: 3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester;4,4,5,5-tetramethyl-2-(3,5-dihydro-2H-thiopyran-4-yl)-1,3,2-dioxaborolane;2H-Thiopyran, 3,6-dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;6-dihydro-2H-thiopyran-4-yl)-4;2-(3,6-dihydro-2H-thiopyran-4-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane;3,6-Dihydro-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-2H-thiopyran;3,6-Dihydrothiopyran-4-boronic acid pinacol ester, 98%;3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (3,6-dihydro-2H-thiopyran-4-yl)boronate
• CAS NO: 862129-81-5
• Molecular Formula: C₁₁H₁₉BO₂S
• Molecular Weight: 226.14
• EINECS: 1592732-453-0
• Product Categories: Organoborons;Organic boronic acid
• Mol File: 862129-81-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 281.1°C at 760 mmHg
• Flash Point: 123.8°C
• Appearance: /Solid
• Density: 1.02g/cm³
• Vapor Pressure: 0.0062mmHg at 25°C
• Refractive Index: 1.484
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester(862129-81-5)
• EPA Substance Registry System: 3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester(862129-81-5)

Safety Data

• Hazardous Substances Data: 862129-81-5(Hazardous Substances Data)

Usage

General Description

3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester is a chemical compound used in organic synthesis. It is a boronic acid pinacol ester derivative that contains a thiopyran ring. 3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester is commonly used as a reagent in chemistry for the formation of carbon-carbon and carbon-heteroatom bonds through cross-coupling reactions. It is known for its ability to participate in Suzuki-Miyaura coupling reactions, which are important in the synthesis of biaryl compounds. Additionally, 3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester has potential applications in medicinal chemistry, as boronic acid derivatives have been studied for their biological activities and therapeutic potential.

InChI:InChI=1/C11H21BO2S/c1-10(2)11(3,4)14-12(13-10)9-5-7-15-8-6-9/h9H,5-8H2,1-4H3

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 121-43-7 Trimethyl borate 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 1072-72-6 Tetrahydrothiopyran-4-one 
• 181180-42-7 3,6-dihydro-2H-thiopyran-4-enol trifluoromethanesulfonate 

Downstream Products

• 862129-83-7 1-(2-{4-[2-(3,6-dihydro-2H-thiopyran-4-yl)-6-methoxy-naphthalen-1-yloxy]-phenoxy}-ethyl)-piperidine 
• 1370535-33-3 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-thiopyran 1,1-dioxide 

Relevant articles and documents

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BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

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