862422-18-2Relevant academic research and scientific papers
Synthesis of a novel series of 4,4-disubstituted 2,3,4,7-tetrahydroazepines
Barberis, Mario,García-Losada, Pablo,Pleite, Sehila,Rodríguez, Juan Ramón,Soriano, José Francisco,Mendiola, Javier
, p. 4847 - 4850 (2007/10/03)
A general, simple and straightforward strategy for the synthesis of a novel series of 4,4-disubstituted 2,3,4,7-tetrahydroazepines is described. This route involves a one-pot Wittig olefination/N-allylation process on a five-membered hemi-aminal followed by a final ring closing metathesis reaction.
