862423-76-5Relevant academic research and scientific papers
Complex aldol reactions for the construction of dense polyol stereoarrays: Synthesis of the C33-C36 region of aflastatin A
Evans, David A.,Glorius, Frank,Burch, Jason D.
, p. 3331 - 3333 (2007/10/03)
(Chemical Equation Presented) Facial selectivity in the addition of boron enolates of α-oxygenated ketones to anti-disposed α,β-bisalkoxy aldehydes is controlled by the aldehyde vicinal diol protecting group. Protection of the diol as an acetonide results in the exclusive formation of the anti-syn-anti stereoarray found in the C33-C36 region of aflastatin A.
