862476-73-1

Upstream product

• 824-94-2 p-methoxybenzyl chloride 
• 81600-93-3 allyl 4,6-di-O-benzylidene-α-D-mannopyranoside 
• 3458-28-4 D-Mannose 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 41308-76-3 allyl α-D-mannopyranoside 
• 127866-65-3 5-[(4-methoxybenzyl)sulfanyl]-1-phenyl-1H-tetrazole 

Downstream Products

• 1040282-33-4 allyl 4,6-O-benzylidene-2-O-[4,6-O-benzylidene-2-O-benzyl-3-O-tri-isopropylsilyloxymethyl-β-D-mannopyranosyl]-3-O-p-methoxybenzyl-α-D-mannopyranoside 
• 862476-84-4 allyl 4,6-O-benzylidene-2-O-[4,6-O-benzylidene-2-O-{4,6-O-benzylidene-2,3-di-O-p-methoxybenzyl-β-D-mannopyranosyl}-3-O-p-methoxybenzyl-α-D-mannopyranosyl]-3-O-p-methoxybenzyl-α-D-mannopyranoside 
• 862476-68-4 allyl 4,6-O-benzylidene-2-O-tert-butyldimethylsilyl-3-O-p-methoxybenzyl-α-D-mannopyranoside 
• 862476-83-3 allyl 4,6-O-benzylidene-2-O-[4,6-O-benzylidene-3-O-p-methoxybenzyl-α-D-mannopyranosyl]-3-O-p-methoxybenzyl-α-D-mannopyranoside 

Relevant academic research and scientific papers

A mild method for the protection of alcohols using a para-methoxybenzylthio tetrazole (PMB-ST) under dual acid-base activation

With a view to expand the repertoire of chemoselective methods applicable to sensitive and multifunctional substrates, the p-methoxybenzylation of alcohols under essentially neutral conditions is reported. This was achieved by the silver triflate (AgOTf) activation of 5-(p-methoxybenzylthio)-1-phenyl-1H-tetrazole (PMB-ST) in the presence of 2,6-di-tert-butyl-4-methylpyridine (DTBMP).

Efficient installation of β-mannosides using a dehydrative coupling strategy

(Chemical Equation Presented) A new coupling procedure for the construction of the challenging β-mannosidic bond is described. Dehydrative mannosylation using 4,6-O-benzylidene mannopyranoses allows for the formation of β-mannosides in excellent yield. Th