86256-87-3Relevant academic research and scientific papers
SYNTHESIS OF ANALOGUES OF THE ANTITUMOR ANTIBIOTIC AT-125 (ACIVICIN)
Stevens, Robert V.,Polniaszek, Richard P.
, p. 743 - 748 (1983)
Several haloisoxazoline analogues of α-amino-3-chloro-4,5-dihydro-5-isoxazole acetic acid (1, AT-125) were prepared by means of 1,3-dipolar cycloaddition methodology.The chemistry of these compounds is discussed, and a possible biological mode of action of AT-125 presented.
