862603-33-6

Upstream product

• 862603-42-7 tert-butyl-[(1R)-1-iodomethyl-oct-7-enyloxy]dimethylsilane 
• 184435-75-4 (5S)-5-methyl-3-phenylsulfanyl-4,5-dihydrofuran-2(3H)-one 
• 2695-47-8 6-Bromo-1-hexene 
• 862604-02-2 (R)-1-iodonon-8-en-2-ol 
• 915314-56-6 (R)-1-chloronon-8-en-2-ol 

Downstream Products

• 862604-04-4 (S)-3-((2R,11R)-2-(tert-Butyl-dimethyl-silanyloxy)-11-{(2S,5R,2'S,5'R)-5'-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-undecyl]-octahydro-[2,2']bifuranyl-5-yl}-11-hydroxy-undecyl)-5-methyl-3-phenylsulfanyl-dihydro-furan-2-one 
• 862603-35-8 (S)-3-((E)-(2R,11R)-2-(tert-Butyl-dimethyl-silanyloxy)-11-{(2S,5R,2'S,5'R)-5'-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-undecyl]-octahydro-[2,2']bifuranyl-5-yl}-11-hydroxy-undec-8-enyl)-5-methyl-3-phenylsulfanyl-dihydro-furan-2-one 

Relevant academic research and scientific papers

Total synthesis of (+)-cis-sylvaticin: Double oxidative cyclization reactions catalyzed by osmium

The double oxidative cyclization of dienes is a viable procedure for making complex natural products containing cis-THF units. A double deprotection/double oxidative cyclization strategy using catalytic osmium tetroxide was used to construct the bishetero

Concise syntheses of the natural products (+)-sylvaticin and (+)-cis-sylvaticin

Two concise syntheses of the natural products cis-sylvaticin and sylvaticin are reported, using oxidative cyclization methodology as the key step. A sequential solvolysis/hydride shift/intramolecular reduction cascade was used to establish the trans stereochemistry of one of the THF rings of sylvaticin.

Stereoselective syntheses of rolliniastatin 1, rollimembrin, and membranacin

A radical cyclization of β-alkoxyvinyl sulfoxides-Pummerer rearrangement-allylation protocol was successfully applied to the synthesis of the threol cis/threol cis/erythro bis-oxolane moiety in rolliniastatin 1 (1), rollimembrin (2), and membranacin (3).