862608-92-2

Basic information

• Product Name: [Al(CH₃)2(CH₂C(O)C₆H₂(CH(CH₃)2)3)]2
• CAS NO: 862608-92-2
• Molecular Weight: 604.872
• Mol File: 862608-92-2.mol

Chemical Properties

• CAS DataBase Reference: [Al(CH₃)2(CH₂C(O)C₆H₂(CH(CH₃)2)3)]2(CAS DataBase Reference)
• NIST Chemistry Reference: [Al(CH₃)2(CH₂C(O)C₆H₂(CH(CH₃)2)3)]2(862608-92-2)
• EPA Substance Registry System: [Al(CH₃)2(CH₂C(O)C₆H₂(CH(CH₃)2)3)]2(862608-92-2)

Safety Data

• Hazardous Substances Data: 862608-92-2(Hazardous Substances Data)

Upstream product

• 2234-14-2 1-(2,4,6-triisopropylphenyl)ethanone 
• 75-24-1 trimethylaluminum 

Relevant articles and documents

Stereoselective synthesis of enones from the reaction of aldehydes with sterically hindered dimethylaluminum enolates

The equimolar reaction between Me3Al and the methyl ketones (2,4,6-R3-C6H2)C(O)CH3, where R = Me or iPr, results in exclusive formation of the enolization products [{Me2AlOC(2,4,6-R3-C6H2)CH 2}2], 1 and 2, upon heating to reflux temperature in toluene solution. The property of Me3Al acting as a base rather than a nucleophile in these reactions is due to the sterically hindered nature of the ketones. Crystallographic analysis of 2 revealed a dimeric complex where the metal centers are bridged by the enolate anions, consistent with the previous studies of 1. Addition of a series of aldehydes to hexane solutions of 1 and 2, followed by heating to reflux for several hours gave enone products in generally high conversions. The presumed aluminum aldolate intermediates were not detected by in situ monitoring studies and are presumably short-lived under the reaction conditions. The enone products from the addition reactions were formed predominantly as the E-isomers with good to excellent stereoselectivities.