862659-22-1Relevant academic research and scientific papers
3,4-SUBSTITUTED PYRROLIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
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Page/Page column 26, (2009/07/18)
The present invention is directed to 3,4-substituted pyrrolidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer'
Imino-ene reaction of N-tosyl arylaldimines with α-methylstyrene: Application in the synthesis of important amines
Pandey, Manoj K.,Bisai, Alakesh,Pandey, Ankur,Singh, Vinod K.
, p. 5039 - 5041 (2007/10/03)
Copper(II) or tin(II) trifluoromethanesulfonate in combination with TMSCl effectively activates a C-H bond for the imino-ene reaction of N-tosylarylaldimines with α-methylstyrene. A wide variety of N-tosylarylaldimines were used to give homoallylamines in
