86282-02-2Relevant academic research and scientific papers
6α-Methylprednisolone derivatives
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, (2008/06/13)
A 6α-methylprednisolone derivative of the general formula: STR1 wherein R1 is a hydrogen atom or stands for the grouping STR2 where R3 is a straight or once-branched chain C1-4 alkyl group, a phenyl group or a lower alkoxy- or alkylthio-methyl group, and R2 is a straight or once-branched chain C1-4 alkyl group, a phenyl group or a lower alkoxy- or alkylthio-methyl group, with the proviso that when R2 is ethyl group, R1 should not be a hydrogen atom or R3 should not be ethyl group. This compound exhibits a strong local antiinflammatory effect and is, therefore, useful as a harmless external antiinflammatory drug for various dermal disorders and also as an antiallergic drug for treating asthma and the like allergic diseases.
Hydrocortisone derivatives, the preparation and use thereof
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, (2008/06/13)
Hydrocortisone derivatives of Formula I STR1 wherein is a single bond or a double bond, n is 1 or 2, R1 is hydrogen or methyl, R2 is alkyl of 1-6 carbon atoms, and R3 is hydrogen or 1-oxoalkyl (alkanoyl) of 2-6 carbon atoms, are pharmacologically active compounds, e.g., as antiinflammatories.
