862823-01-6Relevant academic research and scientific papers
Novel 5-substituted, 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors with antiangiogenic and antitumor activity
Gangjee, Aleem,Zeng, Yibin,Ihnat, Michael,Warnke, Linda A.,Green, Dixy W.,Kisliuk, Roy L.,Lin, Fu-Tyan
, p. 5475 - 5491 (2005)
Recent evidence suggests that combination therapy of cancer with receptor tyrosine kinase (RTK) inhibitors, which are usually cytostatic, with conventional chemotherapeutic agents, which are usually cytotoxic, provide an improved treatment option. We have
