862884-26-2

Upstream product

• 891143-53-6 (4S,5S)-3,4,5,6-tetrahydro-2-(2-bromobenzyl)-4,5-O-isopropylidene-1,2,7-thiadiazepine 1,1-dioxide 
• 100-39-0 benzyl bromide 
• 1233878-54-0 3,4,5,6-tetrahydro-(4S,5S)-2-benzyl-4,5-O-isopropylidene-1,2,7-thiadiazepine 1,1-dioxide 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 835920-63-3 (4S,5S)-O-isopropylidene-1,2,7-thiadiazepine 1,1-dioxide 

Downstream Products

• 891144-30-2 N-Benzyl-2-((3aS,8aS)-7-benzyl-2,2-dimethyl-6,6-dioxo-hexahydro-1,3-dioxa-6λ⁶-thia-5,7-diaza-azulen-5-ylmethyl)-benzamide 
• 891144-23-3 2-((3aS,8aS)-7-Benzyl-2,2-dimethyl-6,6-dioxo-hexahydro-1,3-dioxa-6λ⁶-thia-5,7-diaza-azulen-5-ylmethyl)-N-phenyl-benzamide 
• 891144-46-0 N-[2-((3aS,8aS)-7-Benzyl-2,2-dimethyl-6,6-dioxo-hexahydro-1,3-dioxa-6λ⁶-thia-5,7-diaza-azulen-5-ylmethyl)-phenyl]-2-phenyl-acetamide 
• 891144-38-0 N-[2-((3aS,8aS)-7-Benzyl-2,2-dimethyl-6,6-dioxo-hexahydro-1,3-dioxa-6λ⁶-thia-5,7-diaza-azulen-5-ylmethyl)-phenyl]-benzamide 
• 891144-54-0 N-[2-((3aS,8aS)-7-Benzyl-2,2-dimethyl-6,6-dioxo-hexahydro-1,3-dioxa-6λ⁶-thia-5,7-diaza-azulen-5-ylmethyl)-phenyl]-2-(3-methoxy-phenyl)-acetamide 

Relevant academic research and scientific papers

Synthesis of a small library of non-symmetric cyclic sulfamide HIV-1 protease inhibitors

A set of 11 non-symmetric cyclic sulfamide HIV-1 protease inhibitors were synthesized and evaluated. The use of a key microwave-assisted silver(I) oxide mediated selective mono N-benzylation reaction enabled fast and straightforward synthesis. The Ki

Fast and selective synthesis of novel cyclic sulfamide HIV-1 protease inhibitors under controlled microwave heating

A novel and highly selective silver-promoted monobenzylation method was developed to promote synthesis of nonsymmetrical sulfamide-based HIV-1 inhibitors. Microwave-accelerated palladium-catalyzed N-amide arylation- and aminocarbonylation reactions were e