862972-08-5Relevant academic research and scientific papers
Maleimide cycloadditions by sulfinyldienes: Is the sulfur configuration the only controller of the diastereofacial selectivity?
Aversa, Maria C.,Barattucci, Anna,Bonaccorsi, Paola,Faggi, Cristina,Gacs-Baitz, Eszter,Marrocchi, Assunta,Minuti, Lucio,Taticchi, Aldo
, p. 7719 - 7726 (2007/10/03)
Cyclohexylsulfinyl-3-methyl-1,3-butadienes 5, 6, and 1-[1- (cyclohexylsulfinyl)ethenyl]cyclohexene (7), easily prepared from cyclohexanethiol (1) via transient cyclohexanesulfenic acid (4), were reacted with N-phenylmaleimide under different conditions, at normal and high pressure. The stereochemical outcome of these cycloadditions contributes a better understanding of the relationships among different factors controlling facial diastereoselection.
