863029-48-5Relevant academic research and scientific papers
Asymmetric syntheses of (-)-lentiginosine and an original pyrrolizidinic analogue thereof from a versatile epoxyamine intermediate
Ayad, Tahar,Genisson, Yves,Baltas, Michel
, p. 2626 - 2631 (2005)
Ready access to natural (-)-lentiginosine and its pyrrolizidinic analogue from a chiral vinylic epoxyamine in a straightforward five-step sequence is presented. Careful use of the RCM reaction on aminotriols 5 and 6 constitutes the key feature of the synt
