86310-01-2Relevant academic research and scientific papers
New ketone homoenolate anion equivalents derived from (alkenyl)pentamethyl phosphoric triamides
Grison, Claude,Thomas, Antoine,Coutrot, Frédéric,Coutrot, Philippe
, p. 2101 - 2123 (2007/10/03)
Lithiated ambident anions derived from (1-alkyl-2-propenyl)- or (1-phenyl-2-propenyl)-pentamethyl phosphoric triamides undergo regioselectively γ-reaction with various alkylating reagents and isobutyraldehyde. Further hydrolysis of adducts releases the ketone under acid conditions. Number of synthetic applications clearly show the ketone homoenolate behaviour of these new carbanions.
Stereoselectivity in the Addition of Organocuprates to β-Alkylthio α,β-Enones
Dieter, R. Karl,Silks, Louis A.
, p. 2786 - 2788 (2007/10/02)
Factors affecting the direction and degree of stereoselectivity in the conjugate addition-elimination reaction of organocuprates with β-alkylthio α,β-enones are described.
