86311-20-8Relevant academic research and scientific papers
Photoinduced and Palladium-Catalyzed Remote Desaturation of Amide Derivatives
Jin, Weiwei,Yu, Shouyun
supporting information, p. 6931 - 6935 (2021/09/11)
A photoinduced and palladium-catalyzed remote desaturation of O-acyl hydroxamides to unsaturated amides under mild conditions has been achieved. The formation of the alkyl Pd(II) intermediate by the recombination of alkyl radical and Pd(I) species is critical to achieve this efficient and selective desaturation of alkanes. This reaction features good site-selectivity, is terminal oxidant-free, and produces moderate to excellent yields for a variety of unsaturated amides. Remarkably, this approach enables late-stage desaturation of complex and biologically important molecules.
VINYL ETHERS CONTAINING AN ISOTHIOCYANATE GROUP. XI. N-(2-VINYLOXYETHYL)AMIDES OF CARBOXYLIC ACIDS
Nedolya, N. A.,Gerasimova, V. V.
, p. 220 - 225 (2007/10/02)
The reaction of 2-vinyloxyethyl isothiocyanate with carboxylic acids in the presence of triethylamine leads quantitatively to the N-(2-vinyloxyethyl)amides of the respective acids.Under identical conditions halogenocarboxylic acids (2-chloro-, 2-bromo-, and trifluoroacetic acids) add to the vinyloxy group with the formation of the (2-isothiocyanatoethoxy)ethyl esters of the carboxylic acids.
