863116-52-3Relevant academic research and scientific papers
Synthesis and biological activity of mustard derivatives of combretastatins
Coggiola, Beatrice,Pagliai, Francesca,Allegrone, Gianna,Genazzani, Armando A.,Tron, Gian Cesare
, p. 3551 - 3554 (2005)
A series of chimeric compounds bearing the combretastatin and the nitrogen mustard cores were synthesized. All the compounds were cytotoxic and inhibited tubulin polymerization. When combretastatin was joined to chlorambucil via an ester linkage, the resu
