86318-89-0Relevant articles and documents
A NEW SOLID-PHASE SYNTHESIS OF RIBOOLIGONUCLEOTIDES USING THE 3'-PHOSPHORO-p-ANISIDATE PROTECTING GROUP FOR STEPWISE SYNTHESIS IN THE 3'-DIRECTION
Iwai, Shigenori,Asaka, Miyuki,Inoue, Hideo,Ohtsuka, Eiko
, p. 4618 - 4620 (2007/10/02)
A nonaribonucleotide CAGGUAAGU has been synthesized by the phosphotriester solid-phase method.The 5'-linked 2'-O-tetrahydrofuranyl-N-benzoylcytidine 3'-O-(o-chlorophenyl) phosphate was used as the starting material and chain was elongated in the 3'-direction by removal of the phosphoro-p-anisidate group using isoamyl nitrite under neutal conditions.Keywords - nonaribooligonucleotide; splice site RNA; phosphoro-p-anisidate method; isoamyl nitrite