863211-90-9

Upstream product

• 863211-85-2 2-Methoxy-1-((S)-toluene-4-sulfinyl)-piperidine 
• 1833-53-0 2-(Trimethylsilyloxy)propene 
• 110-89-4 piperidine 
• 1250851-16-1 N-[(S(S))-p-tolylsulfinyl]-5-hexen-1-amine 
• 78-94-4 methyl vinyl ketone 
• 1250851-23-0 (E)-8-N-[(S(S))-p-tolylsulfinyl]-3-octen-2-one 
• 863211-79-4 1-((S)-Toluene-4-sulfinyl)-piperidine 
• 98147-48-9 2-isopropyl-5-methylcyclohexyl 4-methylbenzenesulfinate 

Relevant academic research and scientific papers

N-sulfinyl amines as a nitrogen source in the asymmetric intramolecular aza-michael reaction: Total synthesis of (-)-pinidinol

N-Sulfinyl amines have been successfully employed as nitrogen nucleophiles for the asymmetric intramolecular aza-Michael reaction. The synthetic strategy involves a cross-metathesis reaction followed by the Michael-type cyclization, either in a base-catalyzed two-step procedure or in a tandem fashion. The developed methodology allows access to chiral substituted pyrrolidines and piperidines bearing one or two stereocenters and it has been applied to the synthesis of the piperidine alkaloid (-)-pinidinol.

Anodic oxidation of chiral sulfinylamines: A new route to highly diastereoselective α-alkylation of piperidine

The anodic oxidation of some chiral non-racemic N-arylsulfinyl piperidines was investigated and for the first time α methoxylated sulfinyl piperidines were obtained. The so-formed compounds are equivalent of chiral N-sulfinyliminiums and used as new inter