863224-90-2Relevant academic research and scientific papers
Electrochemical carboxylation of α,α-difluorotoluene derivatives and its application to the synthesis of α-fluorinated nonsteroidal anti-inflammatory drugs
Yamauchi, Yusuke,Fukuhara, Tsuyoshi,Hara, Shoji,Senboku, Hisanori
, p. 428 - 442 (2008/09/16)
Electrochemical carboxylation of α,α-difluorotoluene derivatives resulted in an efficient fixation of carbon dioxide to give the corresponding α-fluorophenylacetic acids in good yields, and this reaction was successfully applied to the synthesis of α-fluorinated nonsteroidal anti-inflammatory drugs (NSAIDs). Georg Thieme Verlag Stuttgart.
