863301-82-0Relevant academic research and scientific papers
Synthesis of novel 5-aryl-2-thio-1,3,4-oxadiazoles and the study of their structure-anti-mycobacterial activities
Macaev, Fliur,Rusu, Ghenadie,Pogrebnoi, Serghei,Gudima, Alexandru,Stingaci, Eugenia,Vlad, Ludmila,Shvets, Nathaly,Kandemirli, Fatma,Dimoglo, Anatholy,Reynolds, Robert
, p. 4842 - 4850 (2007/10/03)
The preparation of novel 5-aryl-2-thio-1,3,4-oxadiazoles 4a-41 and the computer-aided study of their in vitro anti-tubercular activity against Mycobacterium tuberculosis H37Rv (ATCC 27294) are reported. The average accuracy of the electronic-topological method and neural network methods applied to the activity prediction in leave-one-out cross validation is 80%.
