86334-58-9

Basic information

• Product Name: (3S,4S)-3-amino-1-(2,4-dimethoxybenzyl)-4-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)azetidin-2-one
• Synonyms: (3S,4S)-3-amino-1-(2,4-dimethoxybenzyl)-4-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)azetidin-2-one
• CAS NO: 86334-58-9
• Molecular Weight: 336.388
• Mol File: 86334-58-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (3S,4S)-3-amino-1-(2,4-dimethoxybenzyl)-4-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4S)-3-amino-1-(2,4-dimethoxybenzyl)-4-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)azetidin-2-one(86334-58-9)
• EPA Substance Registry System: (3S,4S)-3-amino-1-(2,4-dimethoxybenzyl)-4-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)azetidin-2-one(86334-58-9)

Safety Data

• Hazardous Substances Data: 86334-58-9(Hazardous Substances Data)

Upstream product

• 22323-80-4 (4S)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 86390-73-0 N-<(3S,4S)-cis-1-(2,4-dimethoxybenzyl)-4-<(R)-2,2-dimethyl-1,3-dioxalan-4-yl>-2-oxo-3-azetidinyl>phthalimide 
• 60-34-4 methylhydrazine 
• 20781-20-8 2,4-Dimethoxybenzylamine 
• 88852-09-9 (R,E)-1-(2,4-dimethoxyphenyl)-N-((2,2-dimethyl-1,3-dioxolan-4-yl)methylene)methanamine 

Downstream Products

• 86334-59-0 benzyl ((2S,3S)-1-(2,4-dimethoxybenzyl)-2-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-oxoazetidin-3-yl)-carbamate 
• 86334-63-6 (3S,4S)-3-(benzyloxycarboxamido)-1-(2,4-dimethoxybenzyl)-4-(hydroxymethyl)-2-azetidinone 

Relevant articles and documents

Process Development for the Synthesis of a Monobactam Antibiotic-LYS228

A scalable process for the novel monobactam antibiotic LYS228 has been developed. This paper covers a novel scalable process for producing β-lactam 10 in the multiple kilogram scale. An alternative approach to compound 7 without protecting-group exchange

Antimicrobial 2-oxo-1-azetidinesulphonic acids

Antimicrobial 2-oxo-1-azetidinesulphonic acids of the formula STR1 in which H2 N STR2 represents an amino-substituted thiazolyl group, R1 is lower alkyl which is substituted by carbamoyl, lower alkylsuphonyl, azido, piperidine-carbon

β-Lactams

There is presented optically uniform β-lactams of the formulae STR1 wherein Z is a readily cleavable acyl group, R1 is amino or a group convertible into amino, R2 is hydrogen or a readily cleavable protecting group and R3