863409-40-9Relevant academic research and scientific papers
Copper-catalyzed C-H alkoxylation of azoles
Takemura, Noriaki,Kuninobu, Yoichiro,Kanai, Motomu
, p. 844 - 847 (2013)
We achieved copper-catalyzed intramolecular and intermolecular alkoxylation of azoles. This reaction is a rare example of transition-metal-catalyzed C-H alkoxylation of heteroaromatic compounds. In addition, the alkoxylation reaction proceeded well even i
Novel benzimidazole compounds
-
Paragraph 0144-0146; 0163-0165, (2022/01/12)
The present invention relates to a class of compounds shown in formula (1) and a method of preparation thereof, and compounds of formula (1) and their various constituents, various crystal forms, pharmaceutically acceptable salts as EGFR inhibitors in the
TRICYCLIC COMPOUNDS AS TEC KINASE INHIBITORS
-
Page/Page column 59; 67, (2013/11/05)
The present invention is directed to tricyclic compounds of formula (I) as Tec kinase inhibitors, in particular ITK (interleukin-2 inducible tyrosine kinase) inhibitors. Also provided herein are processes for preparing compounds described herein, intermed
THIOPHENE -2- CARBOXYLIC ACID - (1H - BENZIMIDAZOL - 2 YL) - AMIDE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE TEC KINASE ITK (INTERLEUKIN -2- INDUCIBLE T CELL KINASE) FOR THE TREATMENT OF INFLAMMATION, IMMUNOLOGICAL AND ALLERGIC DISORDERS
-
Page/Page column 142-143, (2010/02/13)
Disclosed are compounds of formula (I): wherein Ar1, Ar2, R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for
