863438-03-3

Basic information

• Product Name: 7-[(4-fluorophenyl)methyl]-4-hydroxy-1-methyl-N-{2-[methyl(methylsulfonyl)amino]ethyl}-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carboxamide
• CAS NO: 863438-03-3
• Molecular Weight: 462.502
• Mol File: 863438-03-3.mol

Chemical Properties

• CAS DataBase Reference: 7-[(4-fluorophenyl)methyl]-4-hydroxy-1-methyl-N-{2-[methyl(methylsulfonyl)amino]ethyl}-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[(4-fluorophenyl)methyl]-4-hydroxy-1-methyl-N-{2-[methyl(methylsulfonyl)amino]ethyl}-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carboxamide(863438-03-3)
• EPA Substance Registry System: 7-[(4-fluorophenyl)methyl]-4-hydroxy-1-methyl-N-{2-[methyl(methylsulfonyl)amino]ethyl}-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carboxamide(863438-03-3)

Safety Data

• Hazardous Substances Data: 863438-03-3(Hazardous Substances Data)

Upstream product

• 863443-05-4 3-amino-5-(4-fluoro-benzyl)-pyridine-2-carboxylic acid methyl ester 
• 1417659-20-1 C₁₉H₁₉FN₂O₅ 
• 778572-84-2 N-(2-aminoethyl)-N-methylmethanesulfonamide 
• 863443-55-4 methyl 5-[(4-fluorophenyl)methyl]-3-(methylamino)-2-pyridinecarboxylate 
• 863443-04-3 methyl 5-[(4-fluorophenyl)methyl]-3-nitro-2-pyridinecarboxylate 

Relevant articles and documents

HIV INTEGRASE INHIBITORS

The present invention features compounds that are HIV integrase inhibitors and therefore are useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC.

Naphthyridinone (NTD) integrase inhibitors: N1 Protio and methyl combination substituent effects with C3 amide groups

Substituent effects of a series of N1 protio and methyl naphthyridinone HIV-1 integrase strand-transfer inhibitors has been explored. The effects of combinations of the N1 substituent and C3 amide groups was extensively studied to compare enzyme inhibitio