863560-90-1

Basic information

• Product Name: acetic acid 4-ethynyl-benzyl ester
• Synonyms: acetic acid 4-ethynyl-benzyl ester
• CAS NO: 863560-90-1
• Molecular Weight: 174.199
• Mol File: 863560-90-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: acetic acid 4-ethynyl-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: acetic acid 4-ethynyl-benzyl ester(863560-90-1)
• EPA Substance Registry System: acetic acid 4-ethynyl-benzyl ester(863560-90-1)

Safety Data

• Hazardous Substances Data: 863560-90-1(Hazardous Substances Data)

Upstream product

• 873-75-6 4-bromobenzenemethanol 
• 21388-92-1 4-bromobenzyl acetate 
• 1041297-60-2 acetic acid 4-trimetylsilanylethynyl-benzyl ester 

Downstream Products

• 1041297-70-4 acetic acid 4-(3,5-dibromo-phenylethynyl)-benzyl ester 
• 1417451-52-5 2,2':6,2-terpyridinethynylbenzyl acetate 
• 681846-20-8 2-ethoxycarbonyl-malonic acid ethyl ester 4-perylen-3-ylethynyl-benzyl ester 
• 681846-19-5 malonic acid ethyl ester 4-perylen-3-ylethynyl-benzyl ester 
• 681846-18-4 (4-perylen-3-ylethynyl-phenyl)-methanol 
• 681846-17-3 acetic acid 4-perylen-3-ylethynyl-benzyl ester 
• 1398771-29-3 (E)-4-(1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-en-2-yl)benzyl acetate 

Relevant articles and documents

Iron-Catalyzed Tertiary Alkylation of Terminal Alkynes with 1,3-Diesters via a Functionalized Alkyl Radical

Direct oxidative C(sp)?H/C(sp3)?H cross-coupling offers an ideal and environmentally benign protocol for C(sp)?C(sp3) bond formations. As such, reactivity and site-selectivity with respect to C(sp3)?H bond cleavage have remained a persistent challenge. Herein is reported a simple method for iron-catalyzed/silver-mediated tertiary alkylation of terminal alkynes with readily available and versatile 1,3-dicarbonyl compounds. The reaction is suitable for an array of substrates and proceeds in a highly selective manner even employing alkanes containing other tertiary, benzylic, and C(sp3)?H bonds alpha to heteroatoms. Elaboration of the products enables the synthesis of a series of versatile building blocks. Control experiments implicate the in situ generation of a tertiary carbon-centered radical species.

RETRACTED ARTICLE: Cooperative melting in caged dimers of rigid small molecule-DNA hybrids

Rigid small-molecule DNA hybrids (rSMDHs) have been synthesized with three DNA strands attached to a rigid tris(phenylacetylene) core. When combined under dilute conditions, complementary rSMDHs form cage dimers that melt at >10 °C higher and much sharper than either unmodified DNA duplexes or rSMDH aggregates formed at higher concentrations. With a 2.97 average number of cooperative duplexes, these caged dimers constitute the first example of cooperative melting in well-defined DNA-small-molecule structures, demonstrating the important roles that local geometry and ion concentration play in the hybridization/dehybridization of DNA-based materials. Copyright