863578-46-5

Usage

Uses

Used in Pharmaceutical Synthesis:
2,4-bis(methoxymethoxy)phenylboronic acid is used as a building block for the synthesis of various pharmaceuticals, leveraging its ability to form stable complexes with diols and other compounds. This property is crucial in creating new drug molecules with specific therapeutic properties.
Used in Organic Compound Synthesis:
In the field of organic chemistry, 2,4-bis(methoxymethoxy)phenylboronic acid is utilized as a key intermediate in the synthesis of complex organic compounds. Its unique reactivity allows for the creation of a wide range of chemical entities with diverse applications.
Used in Chemical Reactions and Processes:
2,4-bis(methoxymethoxy)phenylboronic acid is employed as a versatile tool in various chemical reactions and processes due to its reactivity and capacity to form stable complexes. This makes it instrumental in advancing research and development in chemical engineering and materials science.
Used in Drug Discovery Research:
In drug discovery, 2,4-bis(methoxymethoxy)phenylboronic acid is used as a valuable component in the development of new therapeutic agents. Its unique structure and reactivity contribute to the exploration of novel drug candidates with potential medicinal applications.

Upstream product

• 295788-93-1 1-bromo-2,4-bis(methoxymethoxy)benzene 
• 1344028-46-1 1-iodo-2,4-dimethoxymethoxybenzene 
• 57234-29-4 1,3-bis(methoxymethyl)resorcinol 
• 108-46-3 recorcinol 
• 5419-55-6 Triisopropyl borate 
• 6626-15-9 4-Bromoresorcinol 

Downstream Products

• 863578-47-6 2-(2,4-bismethoxymethoxyphenyl)-3-cyclohexyl-1H-indole-6-carboxylic acid methyl ester 
• 1156-78-1 2',4',5,7-tetrahydroxyisoflavone 
• 98094-87-2 Lupinalbin A 
• 1344028-49-4 2',4',5,7-tetramethoxymethoxyisoflavone 
• 704912-96-9 1-(2,4-bis-methoxymethoxy-phenyl)-3-(3-{4-[3-(2,4-bis-methoxymethoxy-phenyl)-3-oxo-propyl]-2-methoxy-phenoxy}-4-methoxymethoxy-phenyl)-propan-1-one 
• 296763-91-2 3-[2,4-bis(methoxymethoxy)-phenyl]-2-cyclohexen-1-one 
• 863578-48-7 2-(2,4-bismethoxymethoxyphenyl)-3-cyclohexyl-1-[2-(tetrahydropyran-2-yloxy)ethyl]-1H-indole-6-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Enantioselective Total Synthesis of Natural Isoflavans: Asymmetric Transfer Hydrogenation/Deoxygenation of Isoflavanones with Dynamic Kinetic Resolution

A concise and highly enantioselective synthesis of structurally diverse isoflavans from a single chromone is described. The key transformation is a single-step conversion of racemic isoflavanones into virtually enantiopure isoflavans by domino asymmetric transfer hydrogenation/deoxygenation with dynamic kinetic resolution.

NITROGEN-CONTAINING AROMATIC HETEROCYCLYL COMPOUND

The present invention provides a compound having excellent regulating action on blood lipid level. The present invention provides a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof, etc., wherein A represents a 5-membered nitrogen-containing aromatic heterocyclyl group; R1 represents COOH or the like; each R2 represents an alkyl or the like; each R3 represents an optionally substituted phenyl, an optionally substituted phenylalkyl, or the like; m represents 0, 1, 2, or 3; n represents 0 or 1; each of R4, R5, R6, and R7 represents H, an alkyl, or the like; and B represents an optionally substituted naphthyl, an optionally substituted aromatic heterocyclyl, or a group represented by the following formula (II) wherein each of B1 and B2 represents an optionally substituted phenyl or an optionally substituted aromatic heterocyclyl.

Total synthesis of the pyranocoumaronochromone lupinalbin H

The pyranocoumaronochromone lupinalbin H was synthesized in three major steps, which involved preparation of 2′-hydroxygenistein by the Suzuki-Miyaura reaction, followed by oxidative cyclodehydrogenation into lupinalbin A. The final step was the regiospec

Liebeskind-srogl cross coupling mediated synthesis of verbenachalcone

A flexible and scalable total synthesis of verbenachalcone is achieved in eight linear steps from cheap commercially available starting material, 3-(4-hydroxyphenyl)propanoic acid.

Discovery of conformationally constrained tetracyclic compounds as potent hepatitis C virus NS5B RNA polymerase inhibitors

We report a new series of hepatitis C virus NS5B RNA polymerase inhibitors containing a conformationally constrained tetracyclic scaffold. SAR studies led to the identification of 6,7-dihydro-5H-benzo[5,6][1,4]diazepino[7,1-a]indoles (19 and 20) bearing a basic pendent group with high biochemical and cellular potencies. These compounds displayed a very small shift in cellular potency when the replicon assay was performed in the presence of human serum albumin.