98094-87-2Relevant academic research and scientific papers
Facile synthesis of coumaronochromones through palladium-catalyzed intramolecular cross dehydrogenative coupling
Gu, Chang-Xue,Liu, Jian-Guo,Chen, Wen-Wen,Xu, Ming-Hua
, (2021/03/17)
An efficient base-free palladium-catalyzed intramolecular cross dehydrogenative coupling of 2-aryloxy substituted 4-chromenones to access coumaronochromones has been achieved. A range of diversely substituted coumaronochromones can be facilely synthesized in good to excellent yields (up to 90%).
Total synthesis of the pyranocoumaronochromone lupinalbin H
Selepe, Mamoalosi A.,Drewes, Siegfried E.,Van Heerden, Fanie R.
, p. 8654 - 8658 (2011/12/01)
The pyranocoumaronochromone lupinalbin H was synthesized in three major steps, which involved preparation of 2′-hydroxygenistein by the Suzuki-Miyaura reaction, followed by oxidative cyclodehydrogenation into lupinalbin A. The final step was the regiospec
Constrained phytoestrogens and analogues as ERβ selective ligands
Miller, Chris P.,Collini, Michael D.,Harris, Heather A.
, p. 2399 - 2403 (2007/10/03)
A new series of ERbeta (ERβ) selective ligands has been prepared. One of the compounds 6, structurally related to the phytoestrogen apigenin 4, displays a binding preference for ERβ over ERα of over 40-fold. In addition to its binding selectivity, 6 was a
Facile synthesis of polyhydroxycoumaronochromones with quinones: Synthesis of alkylpolyhydroxy- and alkoxycoumaronochromones from 2′-hydroxyisoflavones
Tsukayama, Masao,Oda, Akihiro,Kawamura, Yasuhiko,Nishiuchi, Masaki,Yamashita, Kazuyo
, p. 6163 - 6166 (2007/10/03)
4′,5,7-Trihydroxy- or 8-alkyl-4′,5,7-trihydroxycoumaronochromones were synthesized by oxidative cyclization of the corresponding 2′-hydroxyisoflavones with o-chloranil under mild conditions. By contrast, alkoxycoumaronochromones were synthesized by oxidative cyclization of the corresponding 2′-hydroxyisoflavones with DDQ.
