863647-52-3Relevant academic research and scientific papers
Preparation of poly and diversely substituted N-alkylated and free-NH isoindolin-1-ones
Couture, Axel,Deniau, Eric,Lamblin, Marc,Lorion, Magali,Grandclaudon, Pierre
, p. 1434 - 1437 (2008/02/13)
A variety of diversely substituted N-alkylated and free-NH isoindolin-1-ones have been efficiently prepared by treatment of suitably substituted di- and monoacylated halobenzylamines, respectively, with a lithiated base. Georg Thieme Verlag Stuttgart.
First total synthesis of cichorine and zinnimidine
Moreau, Anne,Couture, Axel,Deniau, Eric,Grandclaudon, Pierre,Lebrun, Stephane
, p. 2305 - 2309 (2007/10/03)
The first total synthesis of the phytotoxins cichorine and zinnimidine is described. The synthetic tactics involve the sequential connection of the dense and diverse functionalities on the aromatic nucleus followed by a Parham cyclization process, giving rise to the lactam unit embedded in the title compound framework. The Royal Society of Chemistry 2005.
