863666-15-3Relevant academic research and scientific papers
From C1 to C3: Copper-Catalyzed gem-Bis(trifluoromethyl)olefination of α-Diazo Esters with TMSCF3
Hu, Jinbo,Hu, Mingyou,Liu, Qinghe,Ni, Chuanfa,Pan, Shitao,Wang, Qian,Xie, Qiqiang
, p. 8507 - 8511 (2020/04/15)
A Cu-catalyzed gem-bis(trifluoromethyl)olefination of α-diazo esters, using TMSCF3 as the only fluorocarbon source, has been developed and provides an exquisite method to access gem-bis(trifluoromethyl)alkenes. This unprecedented olefination pr
Structure-based optimization of phenylbutyrate-derived histone deacetylase inhibitors
Lu, Qiang,Wang, Da-Sheng,Chen, Chang-Shi,Hu, Yuan-Dong,Chen, Ching-Shih
, p. 5530 - 5535 (2007/10/03)
Previously, we developed a strategy to develop a novel class of histone deacetylase (HDAC) inhibitors by tethering short-chain fatty acids with Zn 2+-chelating motifs, which led to N-hydroxy-4-(4-phenylbutyryl-amino) benzamide (HTPB), a hydroxa
