86368-07-2Relevant academic research and scientific papers
ON HYDROBORATION OF 2-ALLYL-1,2,3,4-TETRAHYDROISOQUINOLINE
Ferles, Miloslav,Kafka, Stanislav
, p. 1068 - 1073 (2007/10/02)
Heating of 2-allyl-1,2,3,4-tetrahydroisoquinoline (I) with triethylamine-borane afforded 7,8-benzo-5-aza-1-boraspirodecane (II) which was hydrolyzed with hydrochloric acid to 3-(1,2,3,4-tetrahydro-2-isoquinolyl)propylboronic acid hydrochloride (III).Ethanolysis of II led to the diethyl ester IV.Compounds II and III were oxidized to give 3-(1,2,3,4-tetrahydro-2-isoquinolyl)-1-propanol (V).
