86372-76-1Relevant academic research and scientific papers
Convenient isoprenylation of aldehydes and ketones: Synthesis of (±)-ipsdienol and (±)-ipsenol
Tokuda,Mimura,Yoshioka,Karasawa,Fujita,Suginome
, p. 1086 - 1088 (2007/10/02)
The reaction of 2-bromomethyl-1,4-dibromo-2-butene (1) with various aldehydes and ketones in tetrahydrofuran containing zinc powder under reflux gave the corresponding isoprenylated alcohols 3a-o in one step in good yields. The synthesis of ipsdienol (3e) and ipsenol (3c) was achieved by the present method starting from 3-methyl-2-butenal (2e) and isovaleraldehyde (2c).
New preparation of reactive zinc metal by electrolysis and its use for a facile isoprenylation of aldehydes and ketones
Tokuda, Masao,Mimura, Nobuo,Karasawa, Tamae,Fujita, Hirotake,Suginome, Hiroshi
, p. 7607 - 7610 (2007/10/02)
Reactive zinc metal can be prepared by the electrolysis of a DMF solution containing Et4NClO4 with a platinum cathode and a zinc anode. The reaction of 2-bromomethyl-1, 4-dibromo-2-butene (1) with aldehydes or ketones in the presence of the electrogenarated reactive zinc (EGZn) in DMF at 0 °C gave the corresponding isoprenylated alcohols (3a-3n) in good yields.
