86387-52-2Relevant academic research and scientific papers
Thiohydroximic S-Esters as Reactivators of Organophosporus Inhibited Cholinesterase
Pant, Bhagwat P.,Jaiswal, Devendra K.
, p. 51 - 53 (2007/10/02)
Several 2-diethylaminoethyl thioesters of substituted benzothiohydroximic acids (1a-j) have been synthesised and assigned a Z-configuration on the basis of IR and PMR spectral data.The compounds have been evaluated in vitro with respect of their ability to reactivate tetraethyl pyrophosphate inhibited cholinesterase.The S--4-methylbenzothiohydroximate hydrochloride has shown signigicant reactivation activity.
