863870-79-5

Upstream product

• 863870-72-8 O-3-bromophenyl N,N-diethylcarbamate 
• 88-10-8 N,N-diethylcarbamyl chloride 
• 591-20-8 3-Bromophenol 

Downstream Products

• 52488-36-5 4-bromo-1H-indole 
• 1244651-60-2 N-[3-bromo-2-(hex-1-yn-1-yl)phenyl]-2-hydroxy-2-methylpropanamide 
• 1244651-64-6 N-(3-bromo-2-(hept-1-ynyl)phenyl)-2-hydroxy-2-methylpropanamide 
• 1244651-69-1 N-(3-bromo-2-(2-(trimethylsilyl)ethynyl)phenyl)-2-hydroxy-2-methylpropanamide 
• 1244651-72-6 N-(3-bromo-2-(2-(thiophen-3-yl)ethynyl)phenyl)-2-hydroxy-2-methylpropanamide 
• 1244652-11-6 4-bromo-2-(3-chlorophenyl)-1H-indole 
• 1244651-37-3 N-(3-bromo-2-iodophenyl)-2-hydroxy-2-methylpropanamide 
• 1287792-00-0 2-phenyl-4-(2-phenylethynyl)-1H-indole 
• 1287792-08-8 4-bromo-2-butyl-3-(phenylthio)-1H-indole 
• 1287792-10-2 2-butyl-4-phenyl-1H-indole 
• 1287791-68-7 2-(3-bromo-2-iodophenoxy)-2-methylpropanamide 
• 1332532-82-7 4-((diethylcarbamoyl)oxy)-2-phenylbenzo[b]thiophene 
• 1332532-63-4 3-bromo-2-(phenylethynyl)phenyl diethylcarbamate 

Relevant academic research and scientific papers

An Efficient and Modular Route to C 3?-TunePhos-Type Ligands

An efficient and modular synthetic route to the bidentate C 3?-TunePhos was developed, which allowed tunable steric and electronic effects of the ligands. This novel chemical technology highlights a versatile C 3?-dibromodiphenyl int

NEW BICYCLIC DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I); wherein R1, R2, R3, R4, R5, R6, R7, R8, R14, W, A and n are as defined in the description. Medicaments.

Approaches to the synthesis of 2,3-dihaloanilines. Useful precursors of 4-functionalized-1 H-indoles

2,3-Dihaloanilines have been proved as useful starting materials for synthesizing 4-halo-1H-indoles. Subsequent or in situ functionalization of the prepared haloindoles allows the access to a wide variety of 2,4- or 2,3,4-regioselectively functionalized indoles in good overall yields. As no efficient synthetic routes to 2,3-dihaloanilines have been described in the literature, different approaches to the preparation of these 1,2,3-functionalized aromatic precursors are now presented. The most general one involves a Smiles rearrangement from the corresponding 2,3-dihalophenols and allows the preparation of 2,3-dihaloanilides in a straightforward and synthetically useful manner.

Synthesis of 4-functionalized-1H-indoles from 2,3-dihalophenols

A new synthesis of 4-halo-1H-indoles has been developed from easily available 2,3-dihalophenol derivatives. The key steps are Smiles rearrangement and a one-pot or stepwise Sonogashira coupling/NaOH-mediated cyclization. Subsequent functionalization allows access to a wide variety of 2,4- or 2,3,4-regioselectively functionalized indoles.

Regioselective synthesis of 4- and 7-alkoxyindoles from 2,3-dihalophenols: Application to the preparation of indole inhibitors of phospholipase A 2

(Chemical Equation Presented) An efficient and regioselective synthesis of 4- and 7-alkoxyindoles has been developed from commercially available starting materials such as 3-halophenols and 3-chloroanisole. Directed ortho-metalation followed by two pallad

A new and efficient synthesis of 4-functionalized benzo[6]furans from 2,3-dihalophenols

Tandem Sonogashira coupling/5-endo-dig cyclization reactions on 2,3-dihalophenols suppose a straightforward entry to 4-halobenzo[b]furans, which can be easily transformed into 4-functionalized benzo[b]furans, that are difficult to synthesize by other proc